Tong Bainan, Xiao Jun, Su Guanfang
Department of Ophthalmology, The Second Hospital of Jilin University, Changchun, China.
BMC Ophthalmol. 2018 Oct 26;18(1):277. doi: 10.1186/s12886-018-0923-y.
The present study reported a case of juxtapapillary retinal capillary hemangioma (JRCH) that was successfully treated by two sessions of full-fluence photodynamic treatment (PDT) with good visual outcome.
A 19-year-old male patient presented progressive deterioration of the vision of right eye due to the presence of exudative macular detachment associated with JRCH. The best-corrected visual acuity (BCVA) had decreased from 1.0 to 0.02. The JRCH was treated with two sessions of full-fluence PDT at an interval of 3 months. After the first PDT, the subfoveal fluid was reduced, albeit not completely disappeared. After the second PDT, the subfoveal fluid was successfully displaced. At the 1.5-year follow-up examination, no subfoveal fluid was observed at the macula, and VA improved from a pretherapy level of 0.02-0.8 at 18 months post-treatment.
Resolution of the exudative macular detachment, reduction in papillomacular area fluid, and reduction in the size of the JRCH were observed during the follow-up period. No severe adverse events were observed. Therefore, PDT is potential candidate treatment for relieving exudative macular detachment and recovering VA and reduction in the size of the JRCH.
本研究报告了一例视乳头旁视网膜毛细血管瘤（JRCH）患者，通过两次全剂量光动力疗法（PDT）成功治疗，视力预后良好。
一名19岁男性患者因存在与JRCH相关的渗出性黄斑脱离，右眼视力逐渐下降。最佳矫正视力（BCVA）从1.0降至0.02。对JRCH进行了两次全剂量PDT治疗，间隔3个月。第一次PDT治疗后，黄斑下积液减少，尽管未完全消失。第二次PDT治疗后，黄斑下积液成功排出。在1.5年的随访检查中，黄斑区未观察到黄斑下积液，治疗后18个月时视力从治疗前的0.02提高到0.8。
随访期间观察到渗出性黄斑脱离消退、视乳头黄斑区积液减少以及JRCH体积减小。未观察到严重不良事件。因此，PDT是缓解渗出性黄斑脱离、恢复视力以及减小JRCH体积的潜在候选治疗方法。
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