Kang Lan, Chen Jia Yu, Gao Shao Rong
School of Life Sciences and Technology, Tongji University, Shanghai 200092, China.
Institute for Regenerative Medicine, Shanghai East Hospital, Tongji University,Shanghai 200123, China.
Yi Chuan. 2018 Oct 20;40(10):825-840. doi: 10.16288/j.yczz.18-209.
The research of stem cell field has developed rapidly in recent decades. With the enhancing of China's economic power, the strength of scientific research is steadily increasing, and the stem cell research even has reached international advanced level. Here, we make a historical review of important research in China, focusing on somatic cell nuclear transfer, induced pluripotent stem cells, haploid pluripotent stem cells and early embryo development. The fast development of single cell sequencing will greatly help the understanding of various development process, and the stem cell clinical application will blossom in China in the future.
近几十年来,干细胞领域的研究发展迅速。随着中国经济实力的增强,科研实力稳步提升,干细胞研究甚至已达到国际先进水平。在此,我们对中国的重要研究进行历史回顾,重点关注体细胞核移植、诱导多能干细胞、单倍体多能干细胞和早期胚胎发育。单细胞测序的快速发展将极大地有助于理解各种发育过程,未来干细胞临床应用将在中国蓬勃发展。