Peçanha Arine Santos, Monteiro Alexandra Maria, Gazolla Fernanda Mussi, Madeira Isabel Rey, Bordallo Maria Alice Neves, Carvalho Cecilia N Miranda, Cavalini Luciana Tricai
Universidade do Estado do Rio de Janeiro (UERJ), Rio de Janeiro, RJ, Brazil.
Hospital Universitário Pedro Ernesto da Universidade do Estado do Rio de Janeiro (HUPE-UERJ), Rio de Janeiro, RJ, Brazil.
Radiol Bras. 2018 Sep-Oct;51(5):293-296. doi: 10.1590/0100-3984.2016.0230.
Abstract.
To evaluate, using ultrasound, the distribution of abdominal fat in obese prepubertal children, as well as its possible correlation with metabolic changes due to obesity.
This was a cross-sectional study of prepubescent children: 77 obese children (33 girls and 44 boys), with a mean age of 7.31 years; and 31 normal-weight children (17 girls and 14 boys), with a mean age of 7.32 years. In all of the children, abdominal wall thickness (AWT) and abdominal fat thickness (AFT) were measured by ultrasound. For the evaluation of the associated metabolic alterations, serum levels of glycemia, HDL cholesterol, triglycerides, and insulin were determined.
The obese children presented with greater abdominal fat, predominantly greater AWT, without a significant gender-related difference in AWT or AFT. The homeostasis model assessment of insulin resistance (HOMA-IR) showed a significant direct correlation with AWT and AFT.
In obese prepubertal children, the AWT, as measured by ultrasound, was shown to be more closely related to the HOMA-IR than to the lipid metabolism or glycemia.
摘要。
使用超声评估青春期前肥胖儿童腹部脂肪的分布情况，以及其与肥胖所致代谢变化的可能相关性。
这是一项针对青春期前儿童的横断面研究：77名肥胖儿童（33名女孩和44名男孩），平均年龄7.31岁；以及31名体重正常的儿童（17名女孩和14名男孩），平均年龄7.32岁。对所有儿童均通过超声测量腹壁厚度（AWT）和腹部脂肪厚度（AFT）。为评估相关的代谢改变，测定了血糖、高密度脂蛋白胆固醇、甘油三酯和胰岛素的血清水平。
肥胖儿童腹部脂肪更多，主要是AWT更大，在AWT或AFT方面无显著的性别差异。胰岛素抵抗的稳态模型评估（HOMA-IR）与AWT和AFT呈显著正相关。
在青春期前肥胖儿童中，通过超声测量的AWT与HOMA-IR的关系比与脂质代谢或血糖的关系更为密切。
