Itraconazole treatment of experimental systemic candidiasis in male rats.
作者信息
Yozwiak M L, Galgiani J N
出版信息
J Med Vet Mycol. 1987 Apr;25(2):125-6. doi: 10.1080/02681218780000171.
PMID:3037058
Abstract
After intravenous infection with Candida albicans, rats received daily doses of itraconazole for 3 days. All rats receiving 2.5 mg kg-1 day-1 survived while all rats receiving sham-treatment died. With subsequent reduction of the itraconazole dose to 0.63 mg kg-1 day-1, no survival occurred and mortality rates equalled those of the control group.
摘要
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