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基于一项 1-5 年前瞻性队列研究的牙种植体周围炎预测模型:治疗严重牙周炎患者的牙种植体周围炎。

A nomogram prediction of peri-implantitis in treated severe periodontitis patients: A 1-5-year prospective cohort study.

机构信息

Department of Periodontology, Peking University School and Hospital of Stomatology, Beijing, China.

出版信息

Clin Implant Dent Relat Res. 2018 Dec;20(6):962-968. doi: 10.1111/cid.12686. Epub 2018 Oct 29.

Abstract

BACKGROUND

No nomogram of peri-implantitis was reported before which is valuable for risk-estimating, clinical decision-making, and better-patients-communicating.

PURPOSE

To identify the risk indicators and develop a nomogram prediction model of peri-implantitis in treated severe periodontitis patients.

MATERIALS AND METHODS

A prospective study was conducted on 100 patients with 214 implants. Periodontal and peri-implant parameters were evaluated at implant surgery procedure (T1), and at follow-up (T2). Risk factors were analyzed by logistic regression analyses with generalized estimating equations. Nomogram was developed and the discriminatory ability of the model was analyzed.

RESULTS

The incidence of peri-implantitis at patient-level and implant level were 16% and 11.2% respectively, with no implant lost. The variables associated with peri-implantitis were the PD  ≥ 6 mm (%) > 10%, the implant position, length, and diameter after adjusting for covariates. A nomogram prediction model of peri-implantitis were developed with factors of PD  ≥ 6 mm (%) > 10% and implant placed in posterior. The area under the ROC curves of stepwise model was 0.794.

CONCLUSIONS

The residual pockets and implants position were identified as predictors for the peri-implantitis. The nomogram can be used to estimate the risk of peri-implantitis in treated severe periodontitis patients.

摘要

背景

目前尚无关于种植体周围炎的列线图,而列线图对于风险评估、临床决策和更好的医患沟通非常有价值。

目的

确定种植体周围炎的风险指标,并为治疗严重牙周炎患者开发列线图预测模型。

材料和方法

对 100 名患者的 214 个种植体进行了前瞻性研究。在种植手术时(T1)和随访时(T2)评估牙周和种植体参数。使用广义估计方程对风险因素进行 logistic 回归分析。开发了列线图并分析了模型的判别能力。

结果

患者层面和种植体层面的种植体周围炎发生率分别为 16%和 11.2%,无种植体丢失。与种植体周围炎相关的变量为 PD  ≥ 6mm(%)> 10%,以及调整协变量后的种植体位置、长度和直径。建立了一个种植体周围炎列线图预测模型,其预测因素为 PD  ≥ 6mm(%)> 10%和种植体置于后牙区。逐步模型的 ROC 曲线下面积为 0.794。

结论

残留袋和种植体位置被确定为种植体周围炎的预测因素。列线图可用于评估治疗严重牙周炎患者发生种植体周围炎的风险。

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