Tahaoglu Ali Emre, Dogan Yasemin, Bakir Mehmet Sait, Baglı Ihsan, Peker Nurullah, Cavus Yunus, Togrul Cihan, Tahaoglu Zelal
a Department of Obstetrics and Gynecology , University of Health Sciences Gazi Yasargil Research and Training Hospital , Diyarbakir , Turkey.
J Obstet Gynaecol. 2019 Feb;39(2):259-264. doi: 10.1080/01443615.2018.1499714. Epub 2018 Oct 29.
The management of a caesarean scar pregnancy ranges from conservative medical therapy to surgical treatment. The aim of this study is to present our experience of caesarean scar ectopic pregnancies treated with different modalities and to develop a management algorithm. This retrospective clinical analysis included 21 caesarean scar pregnancies. The clinical data, ultrasonographic characteristics, b-human chorionic gonadotropin concentrations, the treatment options and complications were noted. One patient was managed expectantly, six patients were treated with D and C, seven patients were treated with systemic methotrexate, eight patients underwent a caesarean scar pregnancy removal with a laparoscopy, three patients were treated with a hysteroscopy. Three patients who recieved a methotrexate required additional treatment methods including a laparoscopy, hysteroscopy and D and C. Surgery was successful in all cases. An intra-abdominal haemorrhage from the vessels in the scar area occured in the patient managed expectantly, and a laparatomy and removal was performed. A systemic methotrexate, dilatation and curettage, hysteroscopic resection and laparoscopic resection are feasible methods for scar pregnancy treatment depending on the gestational age, β-hCG level, the type of scar pregnancy and the clinical status of the patient. IMPACT STATEMENT What is already known on this subject? CSP has increased gradually parallel to the increased rates of CS worldwide. There is no treatment consensus on that rare entity. What do the results of this study add? We aimed to present our cases and to discuss a proposal algorithm with further studies. What are the implications of these findings for clinical practice and/or further research? Our cases and proposal algorithm could help to determine the treatment options for CSP.
剖宫产瘢痕妊娠的治疗方法包括从保守的药物治疗到手术治疗。本研究的目的是介绍我们采用不同方式治疗剖宫产瘢痕异位妊娠的经验,并制定一种治疗方案。这项回顾性临床分析纳入了21例剖宫产瘢痕妊娠患者。记录了临床资料、超声特征、β-人绒毛膜促性腺激素浓度、治疗方案及并发症。1例患者采用期待治疗,6例患者行刮宫术,7例患者接受全身甲氨蝶呤治疗,8例患者通过腹腔镜手术切除剖宫产瘢痕妊娠物,3例患者接受宫腔镜治疗。3例接受甲氨蝶呤治疗的患者需要额外的治疗方法,包括腹腔镜手术、宫腔镜手术及刮宫术。所有病例手术均成功。采用期待治疗的患者瘢痕区域血管发生腹腔内出血,遂行剖腹手术并切除妊娠物。根据孕周、β-人绒毛膜促性腺激素水平、瘢痕妊娠类型及患者临床状况,全身甲氨蝶呤治疗、刮宫术、宫腔镜切除术及腹腔镜切除术都是治疗瘢痕妊娠的可行方法。影响声明关于该主题已了解哪些内容?随着全球剖宫产率的上升,剖宫产瘢痕妊娠也逐渐增加。对于这种罕见疾病尚无治疗共识。本研究结果有何新增内容?我们旨在展示我们的病例并讨论一个有待进一步研究的建议方案。这些发现对临床实践和/或进一步研究有何意义?我们的病例和建议方案有助于确定剖宫产瘢痕妊娠的治疗选择。