促肾上腺皮质激素（4-10）对松鼠猴贝赫捷列夫反射的影响。

Effect of ACTH-(4-10) on Bechterew's compensation in squirrel monkeys.

作者信息

Ishii M, Igarashi M

出版信息

ORL J Otorhinolaryngol Relat Spec. 1987;49(2):87-92. doi: 10.1159/000275912.

Abstract

ACTH-(4-10), a fragment of the ACTH without hormonal action, has been known to have effects on learning and memory process. Recently, we have shown that ACTH-(4-10) had marked effects on the balance compensation process after unilateral labyrinthectomy in squirrel monkeys. In this study, we examined the effect of daily administration of ACTH-(4-10) following two-staged bilateral labyrinthectomy. When the locomotor balance function and the slow-phase eye velocity of the spontaneous nystagmus were analyzed, the ACTH-(4-10) groups compensated significantly faster than the control group (p less than 0.05).

摘要

促肾上腺皮质激素（4-10）是一种无激素作用的促肾上腺皮质激素片段，已知其对学习和记忆过程有影响。最近，我们发现促肾上腺皮质激素（4-10）对松鼠猴单侧迷路切除术后的平衡补偿过程有显著影响。在本研究中，我们检查了两阶段双侧迷路切除术后每日给予促肾上腺皮质激素（4-10）的效果。当分析自发眼球震颤的运动平衡功能和慢相眼速度时，促肾上腺皮质激素（4-10）组的代偿明显快于对照组（p小于0.05）。