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通过预先放置小脑蚓部病变实现迷路切除术后的平衡补偿。

Post-labyrinthectomy balance compensation with preplacement of cerebellar vermis lesion.

作者信息

Igarashi M, Ishikawa K

出版信息

Acta Otolaryngol. 1985 Mar-Apr;99(3-4):452-8. doi: 10.3109/00016488509108937.

DOI:10.3109/00016488509108937
PMID:4013734
Abstract

Post-unilateral labyrinthectomy compensation was compared between squirrel monkeys; one group with the pre-placement of posterior vermectomy next group with uvulonodulectomy, and the other group without any vermic lesions. The comparison was made by characterizing behavioral locomotor imbalance (by squirrel monkey platform runway test) and oculomotor imbalance (spontaneous nystagmus). Post-posterior vermectomy + unilateral labyrinthectomy group showed a much slower regainment of locomotor balance function when compared to that after uvulonodulectomy + unilateral labyrinthectomy group (which results was almost identical to that after unilateral labyrinthectomy alone). In contrast, the former group exhibited faster decay in spontaneous nystagmus, whereas the latter group showed delayed reduction of slow phase eye velocity. Thus, posterior vermis could have more functional linkage to the vestibulo-spinal system, whereas, uvula and nodulus, to the vestibulo-oculomotor system.

摘要

在松鼠猴之间比较了单侧迷路切除术后的代偿情况;一组预先进行了后蚓部切除术,另一组进行了小舌-小结切除术,还有一组没有任何蚓部损伤。通过表征行为性运动失衡(通过松鼠猴平台跑道试验)和动眼失衡(自发性眼球震颤)来进行比较。后蚓部切除术后 + 单侧迷路切除术组与小舌-小结切除术后 + 单侧迷路切除术组相比,运动平衡功能的恢复要慢得多(后者的结果与单独进行单侧迷路切除术后的结果几乎相同)。相比之下,前一组的自发性眼球震颤衰减更快,而后一组的慢相眼速度降低延迟。因此,后蚓部与前庭脊髓系统可能有更多的功能联系,而小舌和小结与前庭动眼系统有更多联系。

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