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有氧适能阈值界定儿童和青少年不良心血代谢健康状况。

Aerobic fitness thresholds to define poor cardiometabolic health in children and youth.

机构信息

Department of Sport, Food and Natural Sciences, Faculty of Education, Arts and Sports, Western Norway University of Applied Sciences, Sogndal, Norway.

Department of Sports Medicine, Norwegian School of Sport Sciences, Oslo, Norway.

出版信息

Scand J Med Sci Sports. 2019 Feb;29(2):240-250. doi: 10.1111/sms.13330. Epub 2018 Nov 20.

DOI:10.1111/sms.13330
PMID:30375665
Abstract

Aerobic fitness is an apparent candidate for screening children and youth for poor cardiometabolic health and future risk of cardiovascular disease (CVD). Yet, age- and sex-specific cut points for children and youth determined using a maximal protocol and directly measured peak oxygen consumption (VO ) does not exist. We used a nationally representative sample of 1462 Norwegian children and youth (788 boys and 674 girls aged 8.7-10.4 years and 14.7-16.7 years) who in 2005-2006 performed a maximal cycle ergometer test with direct measurement of VO , along with measurement of several other risk factors for CVD (systolic blood pressure, waist circumference:height ratio, total:high-density lipoprotein cholesterol ratio, triglycerides, Homeostasis Model Assessment for Insulin Resistance). Based on the proportion of children having clustering (least favorable quartile) of 6 (1.6%), ≥5 (5.2%), and ≥4 (10.6%) CVD risk factors, we established the 2nd, 5th, and 10th percentile cut points for VO (mL/kg/min) for children and youth aged 8-18 years. Classification accuracy was determined using the Kappa coefficient (k), sensitivity, and specificity. For boys, the 2nd, 5th, and 10th percentile VO cut points were 33.6-36.4, 36.3-39.8, and 38.7-43.0 mL/kg/min, respectively. For girls, the corresponding cut points were 29.7-29.1, 32.4-31.4, and 34.8-33.5 mL/kg/min Together with BMI, but without more invasive measures of traditional risk factors for CVD, these cut points can be used to screen schoolchildren for poor cardiometabolic health with moderate discriminating ability (k ≤ 0.53).

摘要

有氧适能是筛查儿童和青少年心血管代谢健康不良和未来心血管疾病 (CVD) 风险的明显候选指标。然而,使用最大协议和直接测量的峰值摄氧量 (VO ) 确定的儿童和青少年的年龄和性别特异性切点尚不存在。我们使用了一个全国代表性的挪威儿童和青少年样本(1462 名儿童,788 名男孩和 674 名女孩,年龄为 8.7-10.4 岁和 14.7-16.7 岁;以及 1462 名青少年,788 名男孩和 674 名女孩),他们在 2005-2006 年进行了最大的自行车测力计测试,直接测量了 VO ,并测量了其他几个 CVD 风险因素(收缩压、腰围:身高比、总:高密度脂蛋白胆固醇比、甘油三酯、胰岛素抵抗的稳态模型评估)。根据具有 6(1.6%)、≥5(5.2%)和≥4(10.6%)CVD 风险因素聚类(最不利四分位数)的儿童比例,我们为 8-18 岁的儿童和青少年建立了 VO (mL/kg/min)的第 2、5 和 10 百分位切点。使用 Kappa 系数 (k)、灵敏度和特异性来确定分类准确性。对于男孩,第 2、5 和 10 百分位 VO 切点分别为 33.6-36.4、36.3-39.8 和 38.7-43.0 mL/kg/min。对于女孩,相应的切点分别为 29.7-29.1、32.4-31.4 和 34.8-33.5 mL/kg/min。与 BMI 一起使用,但没有更具侵入性的 CVD 传统风险因素测量,这些切点可以用于筛选学龄儿童的心血管代谢不良,具有中等的辨别能力(k≤0.53)。

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