Keim H, Potthoff P C, Schmidt K, Schiebusch M, Neiss A, Trott K R
Radiother Oncol. 1987 May;9(1):21-6. doi: 10.1016/s0167-8140(87)80215-3.
One hundred and thirty three patients were given radiotherapy after subtotal resection of glioblastoma with different total doses and fractionation schedules including 38 patients receiving continuous accelerated fractionation with 3 fractions of 1.6 Gy per day up to 60 Gy in 2 weeks. Tolerance of the accelerated schedule was as good as of the conventional schedules but overall survival was not improved.
133例胶质母细胞瘤次全切除术后患者接受了不同总剂量和分割方案的放疗,其中38例患者接受持续加速分割放疗,每天3次,每次1.6 Gy,2周内达60 Gy。加速分割方案的耐受性与传统方案相当,但总生存期未得到改善。