Mayer-Scholl Anne, Teifke Jens P, Huber Niclas, Luge Enno, Bier Nadja S, Nöckler Karsten, Ulrich Rainer G
1 German Federal Institute for Risk Assessment, Department for Biological Safety, Max-Dohrn-Str. 8-10, 10589 Berlin, Germany.
2 Friedrich-Loeffler-Institut (FLI), Federal Research Institute for Animal Health, Department of Experimental Animal Facilities and Biorisk Management, Südufer 10, 17493 Greifswald-Insel Riems, Germany.
J Wildl Dis. 2019 Apr;55(2):477-481. doi: 10.7589/2018-05-122. Epub 2018 Oct 30.
Leptospirosis is an occupational risk for military personnel and many cases have been reported worldwide. Rodents are the most important maintenance hosts for Leptospira spp. and may infect both animals and humans. To determine the occurrence and identity of pathogenic Leptospira spp. in rodent and shrew populations in German military camps in Afghanistan, we examined 751 animals ( Mus musculus, Cricetulus migratorius, Meriones libycus, Rattus tanezumi, Crocidura cf. suaveolens, and Suncus etruscus) from four military camps in Northern Afghanistan from 2009-12. Leptospiral DNA was found in 1.1% of the animals and only in Mus musculus. Partial secY sequencing identified Leptospira borgpetersenii and Leptospira kirschneri as infecting genomospecies. Multilocus sequence typing was successful in the L. borgpetersenii samples, which were identified as sequence type 155. The low prevalence we observed suggested that the exposure risk of military personnel to infectious Leptospira spp. in the region is low.
钩端螺旋体病是军事人员面临的职业风险，全球已报告多起病例。啮齿动物是钩端螺旋体属最重要的储存宿主，可能感染动物和人类。为了确定阿富汗德国军营中啮齿动物和鼩鼱种群中致病性钩端螺旋体属的发生情况和种类，我们在2009年至2012年期间检查了阿富汗北部四个军营的751只动物（小家鼠、黑线仓鼠、利比亚沙鼠、黑腹鼠、麝鼩属近缘种和伊氏麝鼩）。在1.1%的动物中发现了钩端螺旋体DNA，且仅在小家鼠中发现。部分secY测序确定博氏钩端螺旋体和克氏钩端螺旋体为感染基因种。多位点序列分型在博氏钩端螺旋体样本中成功进行，这些样本被鉴定为序列型155。我们观察到的低患病率表明该地区军事人员接触感染性钩端螺旋体属的风险较低。
