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髋部骨折疼痛的评估与早期管理:对乙酰氨基酚的影响

Assessment and Early Management of Pain in Hip Fractures: The Impact of Paracetamol.

作者信息

Dixon Ján, Ashton Fiona, Baker Paul, Charlton Karl, Bates Charlotte, Eardley William

机构信息

Department of Trauma & Orthopaedics, James Cook University Hospital, Middlesbrough, England.

出版信息

Geriatr Orthop Surg Rehabil. 2018 Oct 25;9:2151459318806443. doi: 10.1177/2151459318806443. eCollection 2018.

Abstract

INTRODUCTION

As the number of patients sustaining hip fractures increases, interventions aimed at improving patient comfort and reducing complication burden acquire increased importance. Frailty, cognitive impairment, and difficulty in assessing pain control characterize this population. In order to inform future care, a review of pain assessment and the use of preoperative intravenous paracetamol (IVP) is presented.

MATERIALS AND METHODS

Systematic review of preoperative IVP administration in patients presenting with a hip fracture.

RESULTS

Intravenous paracetamol is effective in the early management of pain control in the hip fracture population. There is a considerable decrease in use of breakthrough pain medications when compared with other pain relief modalities. Additionally, IVP reduces the incidence of opioid-induced complications, reduces length of stay, and lowers mean pain scores. Another significant finding of this study is the poor administration of all analgesics to patients with hip fracture with up to 72% receiving no prehospital analgesia.

DISCUSSION

The potential benefits of IVP as routine in the early management of hip fracture-related pain are clear. Studies of direct comparison between analgesia regimes to inform optimum bundles of analgesic care are sparse. This study highlights the need for properly constructed pathway-driven comparator studies of contemporary analgesia regimes, with IVP as a central feature to optimize pain control and minimize analgesia-related morbidity in this vulnerable population.

摘要

引言

随着髋部骨折患者数量的增加,旨在提高患者舒适度和减轻并发症负担的干预措施变得愈发重要。体弱、认知障碍以及疼痛控制评估困难是这一人群的特征。为了为未来的护理提供参考,本文对疼痛评估以及术前静脉注射对乙酰氨基酚(IVP)的使用情况进行了综述。

材料与方法

对髋部骨折患者术前静脉注射对乙酰氨基酚的情况进行系统综述。

结果

静脉注射对乙酰氨基酚在髋部骨折人群疼痛控制的早期管理中有效。与其他止痛方式相比,突破性止痛药物的使用量显著减少。此外,静脉注射对乙酰氨基酚可降低阿片类药物引起的并发症发生率,缩短住院时间,并降低平均疼痛评分。本研究的另一个重要发现是,髋部骨折患者的所有止痛药物给药情况不佳,高达72%的患者在院前未接受止痛治疗。

讨论

静脉注射对乙酰氨基酚作为髋部骨折相关疼痛早期管理常规用药的潜在益处显而易见。关于不同镇痛方案直接比较以确定最佳镇痛护理组合的研究较少。本研究强调需要开展适当构建的、以途径为导向的当代镇痛方案比较研究,以静脉注射对乙酰氨基酚为核心特征,优化这一脆弱人群的疼痛控制并将镇痛相关发病率降至最低。

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