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Genital HIV-1 Shedding With Dolutegravir (DTG) Plus Lamivudine (3TC) Dual Therapy.

作者信息

Gianella Sara, Marconi Vincent C, Berzins Baiba, Benson Constance A, Sax Paul, Fichtenbaum Carl J, Wilkin Timothy, Vargas Millie, Deng Qianqian, Oliveira Michelli F, Moser Carlee, Taiwo Babafemi O

机构信息

Division of Infectious Diseases and Global Public Health, University of California San Diego, La Jolla, CA.

Rollins School of Public Health, Emory University, School of Medicine, Atlanta, GA.

出版信息

J Acquir Immune Defic Syndr. 2018 Dec 15;79(5):e112-e114. doi: 10.1097/QAI.0000000000001863.

DOI:10.1097/QAI.0000000000001863
PMID:30383591
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6231952/
Abstract
摘要

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本文引用的文献

1
Dolutegravir Plus Lamivudine Maintains Human Immunodeficiency Virus-1 Suppression Through Week 48 in a Pilot Randomized Trial.多替拉韦加拉米夫定维持人类免疫缺陷病毒 1 型抑制作用至第 48 周的初步随机试验
Clin Infect Dis. 2018 May 17;66(11):1794-1797. doi: 10.1093/cid/cix1131.
2
ACTG A5353: A Pilot Study of Dolutegravir Plus Lamivudine for Initial Treatment of Human Immunodeficiency Virus-1 (HIV-1)-infected Participants With HIV-1 RNA <500000 Copies/mL.ACTG A5353:多替拉韦加拉米夫定用于治疗 HIV-1 载量<500000 拷贝/mL 的初治 HIV-1 感染者的一项先导研究。
Clin Infect Dis. 2018 May 17;66(11):1689-1697. doi: 10.1093/cid/cix1083.
3
U=U taking off in 2017.U=U于2017年开始实施。
Lancet HIV. 2017 Nov;4(11):e475. doi: 10.1016/S2352-3018(17)30183-2.
4
Longitudinal Viral Dynamics in Semen During Early HIV Infection.早期HIV感染期间精液中的纵向病毒动力学
Clin Infect Dis. 2017 Feb 15;64(4):428-434. doi: 10.1093/cid/ciw784.
5
Latent Toxoplasma Infection and Higher Toxoplasma gondii Immunoglobulin G Levels Are Associated With Worse Neurocognitive Functioning in HIV-Infected Adults.潜伏性弓形虫感染及较高的弓形虫免疫球蛋白G水平与HIV感染成人较差的神经认知功能相关。
Clin Infect Dis. 2016 Dec 15;63(12):1655-1660. doi: 10.1093/cid/ciw655. Epub 2016 Oct 28.
6
HIV-1-RNA Decay and Dolutegravir Concentrations in Semen of Patients Starting a First Antiretroviral Regimen.开始首个抗逆转录病毒治疗方案的患者精液中的HIV-1-RNA衰变与多替拉韦浓度
J Infect Dis. 2016 Nov 15;214(10):1512-1519. doi: 10.1093/infdis/jiw406. Epub 2016 Aug 30.
7
Quantification of HIV RNA and Human Herpesvirus DNA in Seminal Plasma.精液中HIV RNA和人类疱疹病毒DNA的定量分析
Bio Protoc. 2015 May 5;5(9). doi: 10.21769/bioprotoc.1465.
8
Shedding of HIV and human herpesviruses in the semen of effectively treated HIV-1-infected men who have sex with men.高效抗逆转录病毒治疗的 HIV-1 感染男男性行为者精液中 HIV 和人类疱疹病毒的脱落。
Clin Infect Dis. 2013 Aug;57(3):441-7. doi: 10.1093/cid/cit252. Epub 2013 Apr 17.
9
Herpes viruses and HIV-1 drug resistance mutations influence the virologic and immunologic milieu of the male genital tract.疱疹病毒和 HIV-1 耐药突变影响男性生殖道的病毒学和免疫学环境。
AIDS. 2013 Jan 2;27(1):39-47. doi: 10.1097/QAD.0b013e3283573305.
10
Highly active antiretroviral therapy does not completely suppress HIV in semen of sexually active HIV-infected men who have sex with men.高效抗逆转录病毒疗法并不能完全抑制男性同性恋 HIV 感染者精液中的 HIV。
AIDS. 2012 Jul 31;26(12):1535-43. doi: 10.1097/QAD.0b013e328353b11b.