苯炔的 BF<sub>2</sub>-促进、类卡宾、C-H 插入反应。
BF-Promoted, Carbene-like, C-H Insertion Reactions of Benzynes.
机构信息
Department of Chemistry , University of Minnesota , 207 Pleasant Street , SE Minneapolis , Minnesota 55455 , United States.
出版信息
J Am Chem Soc. 2018 Nov 21;140(46):15616-15620. doi: 10.1021/jacs.8b10206. Epub 2018 Nov 8.
Abstract
Boron trifluoride is observed to promote a variety of C-H insertion reactions of benzynes bearing pendant alkyl groups. Computations and various mechanistic studies indicate that BF engages the strained π-bond to confer carbene-like character on the adjacent, noncoordinated benzyne carbon. This represents an unprecedented catalytic role for a non-transition metal such as BF.
摘要
三氟化硼被观察到能够促进带有侧链烷基的苯炔的各种 C-H 插入反应。计算和各种机理研究表明，BF 与应变的 π 键相互作用，赋予相邻的、未配位的苯炔碳原子类似卡宾的特性。这代表了非过渡金属如 BF 前所未有的催化作用。
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