Department of Clinical Medicine and Surgery, University of Veterinary and Animal Sciences, 54600, Lahore, Pakistan.
Department of Clinical Medicine and Surgery, University of Veterinary and Animal Sciences, 54600, Lahore, Pakistan.
Microb Pathog. 2019 Jan;126:116-122. doi: 10.1016/j.micpath.2018.10.033. Epub 2018 Oct 30.
Canine theileriosis is a notorious tick borne piroplasmid infection of wild and domestic canines. The causative agent has not yet been accurately classified. PCR studies revealed that causative agent resembles to Theileria genus and thus provisionally named as Theileria annae. The other Theileria species reported in canines is Theileria annulata, Theileria equi and unnamed Theileria specie. This emergent canine infection is considered to be endemic in most of the European countries. However in Asia this disease has not been reported till date. The vectors responsible for transmission of this disease have not been determined. It has been suggested that DNA of Theileria annae has been detected in hard tick Ixodes hexagonus in Northwestern Spain and several other tick species. Clinically canine theileriosis is characterized by severe weakness, fever, hemoglobinuria and anemia. Recently atovaquone or buparvaquone plus azithromycin therapy showed better clinical efficacy. This comprehensive review is intended to summarize the current knowledge on prevalence and epidemiology of canine theileriosis in different countries of the world and associated tick vectors.
犬泰勒虫病是一种由蜱传播的严重的犬类血液原虫感染病。其病原体尚未被准确分类。PCR 研究表明，病原体与泰勒虫属相似，因此暂命名为安娜泰勒虫。在犬类中报告的其他泰勒虫病是环形泰勒虫、马泰勒虫和未命名的泰勒虫种。这种新出现的犬类感染病被认为在大多数欧洲国家流行。然而，在亚洲，迄今尚未报告该病。负责传播这种疾病的媒介还没有确定。有人建议，在西班牙西北部的硬蜱Ixodes hexagonus 和其他几种蜱类中检测到了安娜泰勒虫的 DNA。临床上，犬泰勒虫病的特征是严重虚弱、发热、血红蛋白尿和贫血。最近，阿托伐醌或巴波喹酮加阿奇霉素治疗显示出更好的临床疗效。本综述旨在总结犬泰勒虫病在世界不同国家的流行情况和相关的蜱类媒介的最新知识。
