Emerg Infect Dis. 2019 Jan;25(1):1111-1115. doi: 10.3201/eid2501.180605. Epub 2019 Jan 17.
We developed an IgM-based ELISA that identifies the dengue virus serotype of recent infections. Dominant serotypes were detectable in 91.1% of samples from travelers and 86.5% of samples from residents of endemic regions; 97.1% corresponded to the serotype identified by PCR. This ELISA enables more accurate reporting of epidemiologic findings.
我们开发了一种基于 IgM 的 ELISA,可识别近期感染的登革热病毒血清型。旅行者样本中,优势血清型的检出率为 91.1%,地方性流行地区居民样本中,优势血清型的检出率为 86.5%;97.1%与 PCR 鉴定的血清型一致。该 ELISA 可更准确地报告流行病学发现。