Pneumology Department, Respiratory Institute (ICR), Hospital Clinic of Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona (UB), SGR 911 - Ciber de Enfermedades Respiratorias (CIBERES), ICREA Academia, Villarroel 170, Barcelona 08036, Spain.
Pneumology Department, Respiratory Institute (ICR), Hospital Clinic of Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona (UB), SGR 911 - Ciber de Enfermedades Respiratorias (CIBERES), ICREA Academia, Villarroel 170, Barcelona 08036, Spain; Department of Pneumology, Hospital Clinic of Barcelona, Villarroel 140, Barcelona 08036, Spain.
Clin Chest Med. 2018 Dec;39(4):753-764. doi: 10.1016/j.ccm.2018.07.008.
The use of adjuvant therapies for community-acquired pneumonia is still in development. Combinations of antibiotics with macrolides seem to be the best option when there is no risk of resistance. The use of corticosteroids is the treatment of choice in patients with severe pneumonia and a high inflammatory response who do not present contraindications for these drugs. Other drugs await confirmation of their benefit and should be used only on exceptional occasions at this time.
辅助疗法在社区获得性肺炎中的应用仍在不断发展。当没有耐药风险时,抗生素与大环内酯类药物联合使用似乎是最佳选择。对于没有这些药物使用禁忌且肺炎严重、炎症反应高的患者,皮质类固醇是治疗的首选。其他药物的疗效仍有待证实,目前仅在特殊情况下使用。