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Detection of gastrin-releasing peptide mRNA in small cell lung carcinomas and medullary thyroid carcinomas using synthetic oligodeoxyribonucleotide probes.

作者信息

Suzuki M, Yamaguchi K, Abe K, Adachi N, Nagasaki K, Asanuma F, Adachi I, Kimura S, Terada M, Taya Y

出版信息

Jpn J Clin Oncol. 1987 Jun;17(2):157-63.

PMID:3039200
Abstract

Human gastrin-releasing peptide (GRP) mRNA was detected in the tumor tissues of medullary thyroid carcinomas and small cell lung carcinomas using synthetic oligodeoxyribonucleotides as hybridization probes. The amount of GRP mRNA was estimated by radiodensitometric hybridization assay. A good correlation was found between the amount of GRP mRNA and the concentration of immunoreactive GRP in the tumor tissues.

摘要

相似文献

1
Detection of gastrin-releasing peptide mRNA in small cell lung carcinomas and medullary thyroid carcinomas using synthetic oligodeoxyribonucleotide probes.
Jpn J Clin Oncol. 1987 Jun;17(2):157-63.
2
Gastrin-releasing peptide-like immunoreactivity in medullary thyroid carcinoma.
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3
Immunoreactive gastrin-releasing peptide as a specific tumor marker in patients with small cell lung carcinoma.免疫反应性胃泌素释放肽作为小细胞肺癌患者的一种特异性肿瘤标志物。
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Production and molecular size heterogeneity of immunoreactive gastrin-releasing peptide in fetal and adult lungs and primary lung tumors.胎儿及成人肺组织和原发性肺肿瘤中免疫反应性胃泌素释放肽的产生及分子大小异质性
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Nonconstitutive expression of the gastrin-releasing peptide autocrine growth system in human small cell lung carcinoma NCI-H345 cells.胃泌素释放肽自分泌生长系统在人小细胞肺癌NCI-H345细胞中的非组成型表达。
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Analysis of the gene and multiple messenger ribonucleic acids (mRNAs) encoding human gastrin-releasing peptide: alternate RNA splicing occurs in neural and endocrine tissue.
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Gastrin releasing peptide in human neuroendocrine tumours.人神经内分泌肿瘤中的胃泌素释放肽
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Immunohistochemical studies on gastrin-releasing peptide- and adrenocorticotropic hormone-containing cells in the human lung.人肺中含胃泌素释放肽和促肾上腺皮质激素细胞的免疫组织化学研究
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Molecular forms of katacalcin, calcitonin gene-related peptide and gastrin-releasing peptide, in a human medullary thyroid carcinoma.
Cancer Res. 1988 May 1;48(9):2412-6.

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