University of Cambridge, Department of Psychiatry, Cambridge, UK.
University of Cambridge, Department of Psychiatry, Cambridge, UK.
Neurosci Biobehav Rev. 2018 Dec;95:396-405. doi: 10.1016/j.neubiorev.2018.10.006. Epub 2018 Oct 28.
We present a review of psychiatric associations with comorbid mental and behavioural disorders affecting people with Prader-Willi syndrome (PWS). This literature review suggests that some assumptions about psychiatric associations of PWS behaviours are unjustified (eg skin picking as OCD) and that genetic aetiology should be considered when making associations between PWS mental and behavioural disorders and psychiatric disorders in the general populationThe literature review also demonstrates the limitations of the studies in terms of small numbers, non-representativeness, and lack of replication.
我们回顾了合并影响 Prader-Willi 综合征（PWS）患者的精神和行为障碍的精神疾病关联。这一文献综述表明，一些关于 PWS 行为的精神疾病关联的假设是不合理的（例如，将抓挠皮肤视为强迫症），在将 PWS 精神和行为障碍与普通人群中的精神障碍联系起来时，应该考虑遗传病因。文献综述还表明，这些研究在数量少、无代表性和缺乏复制性方面存在局限性。
