Zhang Jinlei, Pan Aixing, Zhou Li, Yu Jingyi, Zhang Xiao
Department of Orthopaedics, Zhoukou City Central Hospital, The Affiliated Hospital of Xinxiang Medical College, Zhoukou Shi, China.
Department of Orthopaedics, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
Arch Med Sci. 2018 Oct;14(6):1432-1438. doi: 10.5114/aoms.2018.74890. Epub 2018 Apr 6.
This study was conducted to compare the clinical effects of unilateral pedicle screw fixation and interbody fusion with PEEK cage (UPSFC) and standalone expandable fusion cage (SAEFC) on unilateral lumbar disc herniation.
From September 2011 to July 2014, a respective investigation was performed on 130 lumbar disc herniation patients treated with SAEFC or UPSFC. The hospital stay, operating time, blood loss, Japanese orthopaedic association scores (JOA), and visual analogue score (VAS) in the two groups were compared using Student's -test.
The average of follow-up time was 25.6 ±6.4 and 25.2 ±5.8 months, respectively. No significant difference in the postoperative hospitalizsation, intraoperative blood loss, operative time, and postoperative fusion rate was detected between the two groups. VAS score in the UPSFC group was significantly lower than in the SAEFC group at 6 and 12 months after operation ( = 0.014, = 0.004). X-ray images indicated that the subsidence rate was 8.1% (5/62) in the SAEFC group, while no subsidence was detected in UPSFC group 12 month after operation.
Both SAEFC and UPSFC are effective techniques. UPSFC may be a better choice for patients with lumbar disc herniation and unilateral limb symptoms of nerve root in view of the advantages of better low back pain relief and low subsidence rate.
本研究旨在比较单侧椎弓根螺钉固定联合聚醚醚酮椎间融合器(UPSFC)与单独使用可扩张融合器(SAEFC)治疗单侧腰椎间盘突出症的临床效果。
2011年9月至2014年7月,分别对130例接受SAEFC或UPSFC治疗的腰椎间盘突出症患者进行调查。采用t检验比较两组患者的住院时间、手术时间、失血量、日本骨科协会评分(JOA)和视觉模拟评分(VAS)。
两组患者的平均随访时间分别为25.6±6.4个月和25.2±5.8个月。两组患者术后住院时间、术中失血量、手术时间和术后融合率差异均无统计学意义。术后6个月和12个月时,UPSFC组的VAS评分显著低于SAEFC组(P = 0.014,P = 0.004)。X线片显示,SAEFC组术后12个月的下沉率为8.1%(5/62),而UPSFC组未发现下沉。
SAEFC和UPSFC都是有效的治疗技术。鉴于UPSFC在缓解腰痛和低下沉率方面的优势,对于伴有单侧神经根症状的腰椎间盘突出症患者可能是更好的选择。