Ünal Yılmaz
Department of General Surgery, Ankara Training and Research Hospital, Ankara-Turkey.
Ulus Travma Acil Cerrahi Derg. 2018 Sep;24(5):434-439. doi: 10.5505/tjtes.2018.91661.
The aim of this study was to investigate the effectiveness of the immature granulocyte (IG) count (IGC) and percentage (IG%) in both diagnosing acute appendicitis (AA) and discriminating between simple appendicitis (SA) and complicated appendicitis (CA).
This study was carried out using the data of 438 adult patients who underwent an appendectomy. Demographic details, the preoperative white blood cell (WBC) count, neutrophil/lymphocyte ratio (NLR), IGC and IG%, operation findings, and pathology results were assessed retrospectively. The patients were grouped as AA and normal appendix (NA) according to the pathology reports, and the AA cases were subdivided into SA and CA groups according to the intraoperative findings.
WBC, NLR, IGC, and IG% were significant parameters in the diagnosis of AA. The area under the receiver operating characteristic curve (AUROC: 0.795), sensitivity (55.5%) and specificity (96.1%) values of IGC were higher than the other parameters. All of the parameters were also significant for a CA diagnosis; however, the value of IG% in a CA diagnosis was stronger than the other parameters (IG% AUROC: 0.979, sensitivity: 94.4%, specificity: 97.9%).
The IG value is a fast, easily available, and reliable parameter in both diagnosing AA and discriminating between SA and CA.
本研究旨在探讨未成熟粒细胞（IG）计数（IGC）和百分比（IG%）在诊断急性阑尾炎（AA）以及区分单纯性阑尾炎（SA）和复杂性阑尾炎（CA）方面的有效性。
本研究采用了438例行阑尾切除术的成年患者的数据。回顾性评估了人口统计学细节、术前白细胞（WBC）计数、中性粒细胞/淋巴细胞比值（NLR）、IGC和IG%、手术结果及病理结果。根据病理报告将患者分为AA组和正常阑尾（NA）组，AA病例根据术中发现再细分为SA组和CA组。
WBC、NLR、IGC和IG%是诊断AA的重要参数。IGC的受试者工作特征曲线下面积（AUROC：0.795）、敏感性（55.5%）和特异性（96.1%）值高于其他参数。所有参数对CA诊断也具有显著性；然而，IG%在CA诊断中的价值比其他参数更强（IG%的AUROC：0.979，敏感性：94.4%，特异性：97.9%）。
IG值在诊断AA以及区分SA和CA方面是一个快速、易于获取且可靠的参数。
