C. Eugene Bennett Department of Chemistry , West Virginia University , Morgantown , West Virginia , United States.
Org Lett. 2018 Nov 16;20(22):7216-7219. doi: 10.1021/acs.orglett.8b03144. Epub 2018 Nov 5.
A nickel-catalyzed oxidative decarboxylative annulation reaction of simple benzamides and (hetero)aromatic carboxylates has been developed. This reaction provides access to a large array of phenanthridinones and their heterocyclic analogues, highlighting the utility and versatility of oxidative decarboxylative coupling strategies for C-C bond formation.
一种镍催化的简单苯甲酰胺和(杂)芳基羧酸酯的氧化脱羧环化反应已经被开发出来。该反应提供了大量的菲啶酮及其杂环类似物,突出了氧化脱羧偶联策略在 C-C 键形成中的实用性和多功能性。