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自体骨、多孔聚乙烯与定制钛网颅骨修补术:108例患者的回顾性研究

Cranioplasty Using Autologous Bone versus Porous Polyethylene versus Custom-Made Titanium Mesh : A Retrospective Review of 108 Patients.

作者信息

Kim Jun-Ki, Lee Sang-Bok, Yang Seo-Yeon

机构信息

Department of Neurosurgery, Uijeongbu St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Uijeongbu, Korea.

出版信息

J Korean Neurosurg Soc. 2018 Nov;61(6):737-746. doi: 10.3340/jkns.2018.0047. Epub 2018 Oct 30.

Abstract

OBJECTIVE

The purpose of this study was to compare the cosmetic outcome and complications after cranioplasty (CP) due to three different implant materials, and analyze the mean implant survival and cumulative survival rate based on these results.

METHODS

We reviewed 108 patients retrospectively who underwent CP between January 2014 and November 2016. Autologous bone (AB; 45 patients) and synthetic materials with porous polyethylene (PP; 32 patients) and custom-made 3-dimensional printed titanium mesh (CT; 31 patients) were used as implants.

RESULTS

Regardless of implanted materials, more than 89.8% of the CP patients were satisfied with the cosmetic outcome. No statistically significant difference was observed among the three groups. The overall postoperative complication rates of each group were 31.1% in the AB group, 15.6% in the PP group and 3.2% in the CT group. The CT group showed lower complication rates compared with AB and PP groups (χ2-test : AB vs. PP, p=0.34; AB vs. CT, p=0.00; PP vs. CT, p=0.03). The AB and PP groups demonstrated a higher post-CP infection rate (11.1% and 6.3%) than the CT group (3.2%). However, no significant difference in the incidence of post-CP infection was observed among the three groups. The PP and CT groups demonstrated a higher mean implant survival time and cumulative survival rate than the AB group at the last follow-up (p<0.05).

CONCLUSION

In comparison with AB and PP, cranioplasty with CT shows benefits in terms of lower post-CP complication, less intraoperative bleeding loss, shorter operation time and in-hospital stay. The PP and CT groups showed higher implant survival time and cumulative survival rate compared with the AB group.

摘要

目的

本研究旨在比较三种不同植入材料用于颅骨成形术(CP)后的美容效果及并发症,并基于这些结果分析平均植入物存活率和累积存活率。

方法

我们回顾性分析了2014年1月至2016年11月期间接受CP的108例患者。植入物采用自体骨(AB;45例患者)、多孔聚乙烯合成材料(PP;32例患者)和定制三维打印钛网(CT;31例患者)。

结果

无论植入何种材料,超过89.8%的CP患者对美容效果满意。三组之间未观察到统计学上的显著差异。AB组术后总体并发症发生率为31.1%,PP组为15.6%,CT组为3.2%。与AB组和PP组相比,CT组并发症发生率较低(χ2检验:AB组与PP组,p = 0.34;AB组与CT组,p = 0.00;PP组与CT组,p = 0.03)。AB组和PP组CP后感染率(分别为11.1%和6.3%)高于CT组(3.2%)。然而,三组之间CP后感染发生率无显著差异。在最后一次随访时,PP组和CT组的平均植入物存活时间和累积存活率高于AB组(p < 0.05)。

结论

与AB组和PP组相比,CT颅骨成形术在降低CP后并发症、减少术中失血量、缩短手术时间和住院时间方面具有优势。与AB组相比,PP组和CT组的植入物存活时间和累积存活率更高。

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