Department of Family Medicine, American University of Beirut Medical Center, Beirut, Lebanon
Department of Family Medicine, American University of Beirut Medical Center, Beirut, Lebanon.
Postgrad Med J. 2018 Nov;94(1117):647-652. doi: 10.1136/postgradmedj-2018-136035. Epub 2018 Nov 5.
Dementia is projected to become a global health priority but often not diagnosed in its earlier preclinical stage which is mild cognitive impairment (MCI). MCI is generally referred as a transition state between normal cognition and Alzheimer's disease. Primary care physicians play an important role in its early diagnosis and identification of patients most likely to progress to Alzheimer's disease while offering evidenced-based interventions that may reverse or halt the progression to further cognitive impairment. The aim of this review is to introduce the concept of MCI in primary care through a case-based clinical review. We discuss the case of a patient with MCI and provide an evidence-based framework for assessment, early recognition and management of MCI while addressing associated risk factors, neuropsychiatric symptoms and prognosis.
痴呆症预计将成为全球卫生重点，但在其早期临床前阶段（即轻度认知障碍，MCI）往往未被诊断出来。MCI 通常被认为是正常认知和阿尔茨海默病之间的过渡状态。初级保健医生在其早期诊断和识别最有可能进展为阿尔茨海默病的患者方面发挥着重要作用，同时提供基于证据的干预措施，这些措施可能会逆转或阻止认知障碍的进一步进展。本综述的目的是通过基于案例的临床回顾，在初级保健中介绍 MCI 的概念。我们讨论了一位 MCI 患者的病例，并提供了一个基于证据的评估、早期识别和管理 MCI 的框架，同时解决了相关的危险因素、神经精神症状和预后。
