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从果实和根提取物中分离得到的香豆素和黄酮类化合物。

Coumarins and flavones from the fruit and root extracts of .

机构信息

a Center of Chemical Innovation for Sustainability (CIS), Mae Fah Luang University , Chiang , Rai , Thailand.

b School of Science, Mae Fah Luang University , Chiang , Rai , Thailand.

出版信息

Nat Prod Res. 2019 Oct;33(20):2945-2950. doi: 10.1080/14786419.2018.1510400. Epub 2018 Nov 6.

Abstract

A phytochemical investigation of the fruit and root extracts of resulted in the isolation and identification of a new compound, integerravone (), together with 23 known compounds (-). Their structures were characterized by spectroscopic methods as well as comparisons made from the literature. Compounds , -, - and - were evaluated for their cytotoxicities against the colon cancer cell line, HCT116. All of them were inactive at 50 M. Most of the phenolic compounds were evaluated for their antioxidant activity using the DPPH assay. Compounds and - showed antioxidant activity with IC values ranging from 24.83-135.05 M.

摘要

从 的果实和根提取物中进行的植物化学研究,分离并鉴定出一种新化合物,即 integerravone (),以及 23 种已知化合物 (-)。通过光谱方法以及与文献的比较确定了它们的结构。评估了化合物 、-、-和 - 对结肠癌细胞系 HCT116 的细胞毒性。在 50 μM 时,它们均无活性。使用 DPPH 测定法评估了大多数酚类化合物的抗氧化活性。化合物 和 - 表现出抗氧化活性,IC 值范围为 24.83-135.05 μM。

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