Division of Pharmaceutical Sciences, School of Pharmacy, University of Wisconsin-Madison, Madison, WI 53705, USA.
Division of Pharmaceutical Sciences, School of Pharmacy, University of Wisconsin-Madison, Madison, WI 53705, USA.
Dev Cell. 2018 Nov 5;47(3):261-262. doi: 10.1016/j.devcel.2018.10.022.
Steroid hormones have long been thought to enter target cells via passive diffusion through the plasma membrane. Now, reporting in Developmental Cell, Okamoto et al. (2018) demonstrate that, at least for Drosophila, steroid hormones require a protein transporter for cellular entry.
甾类激素长期以来一直被认为通过质膜的被动扩散进入靶细胞。现在,Okamoto 等人在《发育细胞》杂志上报道(2018),至少对于果蝇而言,甾类激素进入细胞需要一种蛋白质转运体。