Department of Biostatistics, Colorado School of Public Health, 13001 E 17th Place, Aurora, CO 80045, USA.
Department of Neurology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA.
Obstet Gynecol Clin North Am. 2018 Dec;45(4):613-628. doi: 10.1016/j.ogc.2018.07.004. Epub 2018 Oct 25.
Key cycle changes occur as women transition from reproductive life to menopause, and they can be roughly linked to menopausal staging. It is important to understand the types of studies that inform the current knowledge. Patterns of symptoms within menstrual cycles (sleep, headache) generally favor worsening in association with the perimenstrual phase of the cycle, and patterns of chronic symptoms, such as hot flashes and adverse mood, appear to be worse when hormones are more variable.
女性从生育期过渡到绝经期时,关键周期会发生变化,这些变化大致与绝经分期相关。了解为现有知识提供信息的研究类型很重要。月经周期内症状(睡眠、头痛)的模式通常与周期的经前期阶段加重有关,而慢性症状(如热潮红和不良情绪)的模式似乎在激素变化更大时更严重。