Cancer. 1987 Sep 15;60(6):1400-11. doi: 10.1002/1097-0142(19870915)60:6<1400::aid-cncr2820600639>3.0.co;2-w.
The Liver Cancer Study Group of Japan statistically analyzed 4658 cases of primary liver cancer diagnosed from January 1, 1980 to December 31, 1981 in over 400 hospitals throughout the country. The study group comprised 2038 cases of hepatocellular carcinoma, 146 of cholangiocarcinoma, 33 of mixed carcinoma, 30 of hepatoblastoma, six of sarcoma, and 33 others. In 2286 cases (49.1%) a histologic diagnosis was available. The survey, based mostly on the histologically proven cases, describes histologic features of the tumors, grade of anaplasia and growth patterns of the tumor cells, pathology in noncancerous portions of the liver, distant metastases, medical history, frequency of hepatitis in the history, frequency of positive HBsAg and anti-HBs, age distribution, subjective symptoms, radiographic features (angiogram, scintiscan, computed tomography), ultrasonography, surgical procedures, extent of hepatic resection, and survival.
日本肝癌研究小组对1980年1月1日至1981年12月31日期间全国400多家医院诊断出的4658例原发性肝癌病例进行了统计分析。研究小组包括2038例肝细胞癌、146例胆管癌、33例混合癌、30例肝母细胞瘤、6例肉瘤以及33例其他类型。2286例(49.1%)有组织学诊断结果。该调查主要基于组织学确诊病例,描述了肿瘤的组织学特征、间变程度和肿瘤细胞的生长模式、肝脏非癌部分的病理情况、远处转移、病史、既往肝炎发生频率、HBsAg和抗-HBs阳性频率、年龄分布、主观症状、影像学特征(血管造影、闪烁扫描、计算机断层扫描)、超声检查、手术程序、肝切除范围以及生存率。