First Department of Surgery, Faculty of Medicine, Kyoto University, Japan.
Ann Surg. 1990 Mar;211(3):277-87.
The Liver Cancer Study Group of Japan analyzed statistically 12,887 cases of primary liver cancer diagnosed from January 1, 1982 to December 31, 1985 in more than 500 institutes throughout the country. The study was based on the answers to 258 questions. There were 4354 cases of hepatocellular carcinoma, 256 cases of cholangiocellular carcinoma, 49 cases of mixed carcinoma, 22 cases of hepatoblastoma, 10 cases of sarcoma, and 74 other cases. The survey and analysis, based mainly on 4765 histologically proved cases, included gross anatomic and histologic features of the tumors, pathology of the noncancerous portion, distant metastases, past medical history, frequency of positive Hepatitis B surface antigen and Hepatitis B surface antibody, age distribution, various diagnostic procedures, surgical procedures, and survival rate in relation to operative curability and tumor stage.
日本肝癌研究小组对1982年1月1日至1985年12月31日期间全国500多家机构诊断出的12887例原发性肝癌病例进行了统计分析。该研究基于对258个问题的回答。其中肝细胞癌4354例,胆管细胞癌256例,混合癌49例,肝母细胞瘤22例,肉瘤10例,其他74例。主要基于4765例经组织学证实的病例进行的调查和分析,包括肿瘤的大体解剖和组织学特征、非癌部分的病理、远处转移、既往病史、乙肝表面抗原和乙肝表面抗体阳性率、年龄分布、各种诊断方法、手术方法以及与手术可治愈性和肿瘤分期相关的生存率。