《“QUAD Shot”在肛管鳞癌中的应用：附 1 例病例报告并文献复习》。
The Use of "QUAD Shot" in Anal Canal Squamous Cell Carcinoma: A Case Study With Review of the Literature.
机构信息
Department of Radiation Oncology, University of Texas Medical Branch at Galveston, Galveston, Texas, USA.
Department of Radiation Oncology, University of Texas Medical Branch at Galveston, Galveston, Texas, USA.
出版信息
J Pain Symptom Manage. 2019 Feb;57(2):341-345. doi: 10.1016/j.jpainsymman.2018.10.512. Epub 2018 Nov 4.
CONTEXT
Patients with locoregional anal carcinoma who do not qualify for standard definitive chemoradiation are candidates for a short course of palliative hypofractionated radiotherapy such as QUAD Shot.
METHODS
A 57-year-old man with massive locoregional squamous cell carcinoma of the anal canal was treated with QUAD Shot (14.8 Gy in four fractions over two consecutive days) repeated every four weeks for a total of two courses.
RESULTS
He reported symptomatic relief following each course of radiation. In regard to his first QUAD Shot, his pain was 10/10 in severity at the time of admission and 4/10 at the time of discharge. In regard to his second QUAD Shot, his pain was 8/10 at the time of admission and 0/10 at the time of discharge. He did not experience any treatment-related toxicity. He passed away 15 weeks after the first course.
CONCLUSION
QUAD Shot is both efficacious and safe for palliation in patients with anal carcinoma.
背景
不符合标准根治性放化疗条件的局部晚期肛门癌患者，可选择短程姑息性低分割放疗，如 QUAD Shot。
方法
一名 57 岁男性，患有巨大的局部晚期肛门管鳞状细胞癌，接受 QUAD Shot（14.8Gy，4 次分割，连续 2 天）治疗，每 4 周重复一次，共进行 2 个疗程。
结果
他在每次放疗后都报告症状缓解。就他的第一次 QUAD Shot 而言，他入院时的疼痛严重程度为 10/10，出院时为 4/10。就他的第二次 QUAD Shot 而言，他入院时的疼痛严重程度为 8/10，出院时为 0/10。他没有出现任何与治疗相关的毒性反应。他在第一个疗程后 15 周去世。
结论
QUAD Shot 对肛门癌患者的缓解具有疗效和安全性。
Zotero 插件