Kaiser R, Kloppenburg W, Ehmke H, Schwenk H
Geburtshilfe Frauenheilkd. 1987 Jun;47(6):410-3. doi: 10.1055/s-2008-1036146.
Up to 1979 growth was inhibited with hormones in 43 girls in puberty with constitutional gigantism. The average reduction in size as compared to the calculated final body height was 7.5 cm, treatment having been started at a skeletal age of 12.3 years and with a treatment duration of 1.4 years. In over 90% of the cases, the first spontaneous menstruation after termination of therapy occurred within three months. During the first two years, cycles were likewise regular in 90% of the cases, with a duration of 4 +/- 1 weeks. Ovarian function in adolescence was thus found not to be impaired, but rather to be more stable as compared to the total population. It may be concluded from this that the preconditions for future fertility can be regarded as favorable.
截至1979年，43名青春期体质性巨人症女孩使用激素抑制生长。与计算得出的最终身高相比，平均身高降低了7.5厘米，治疗开始时的骨骼年龄为12.3岁，治疗持续时间为1.4年。超过90%的病例在治疗结束后的三个月内出现首次自然月经。在最初两年中，90%的病例月经周期同样规律，持续时间为4±1周。因此发现青春期的卵巢功能未受损害，与总人口相比反而更稳定。由此可以得出结论，未来生育的前提条件可以认为是有利的。
