Investigation of neurodegenerative and inflammatory processes in sleep bruxism.

: The present study aimed to evaluate the anxiety and optical coherence tomography (OCT) findings in patients with sleep bruxism (SB) and to develop objective measurements to assess the neurodegenerative and inflammatory processes associated with this disease. : A group of 40 SB patients were compared with a control group consisting of 40 healthy individuals (without SB). Anxiety results and the OCT measurements of retinal nerve fiber layer (RNFL), ganglion cell layer (GCL), inner plexiform layer (IPL), and choroidal thickness were assessed in both groups. : Anxiety values in the bruxism group were significantly higher than those in the control group. The measurements of RNFL, IPL, and GCL in the bruxism group were significantly lower than the control group, whereas the choroidal thickness was significantly higher. : According to literature, this is the first study that analyzed the changes in the retinal structures in bruxism, which revealed that SB is a neurodegenerative and inflammatory process.