Brink Monique, Steenbakkers Arjan, Holla Micha, de Rooy Jacky, Cornelisse Simon, Edwards Michael J, Prokop Mathias
Department of Radiology and Nuclear Medicine, Radboud University Medical Centre Nijmegen, huispost 780, PO Box 5601, 6500 HB, Nijmegen, The Netherlands.
Department of Surgery, Radboud University Medical Centre Nijmegen, Nijmegen, The Netherlands.
Skeletal Radiol. 2019 Jun;48(6):949-957. doi: 10.1007/s00256-018-3097-z. Epub 2018 Nov 8.
To evaluate accuracy of fracture detection and therapeutic impact of a single-shot CT protocol as a primary imaging tool in all patients with clinical suspicion of wrist injury, and evaluate the resulting impact on therapy.
We performed a single-institution study on all patients with suspicion of fractures of the wrist and carpus. All patients underwent conventional radiography, thereafter single-shot wrist CT, and then 1-year follow-up. Physicians and radiologists prospectively scored likelihood of fracture presence on a five-point scale before and after CT. Three surgeons proposed a treatment regimen (functional, cast, reduction, or operative) based on clinical and radiological data, first with knowledge of conventional radiography, and then with knowledge of CT. The reference standard for fracture presence was based on all data. We performed receiver operating characteristic (ROC) analyses and calculated proportion of wrists with treatment changes due to CT imaging.
Ninety-eight patients participated (63% female, mean age 53, range, 18-87 years old) with 100 wrist CTs. Conventional radiography detected true-positive fractures in 45, and CT in 61 wrists. The areas under the curve for fracture detection were 0.85 (95% CI 0.77-0.93) for conventional radiography and 0.97 (95% CI 0.93-1.00) for CT. Treatment changed in 24 (24%, 95% CI 16-33%) - 31 (31%, 95% CI 23-41%) wrists, mostly involving a decrease in the rate of cast immobilization.
Single-shot CT in patients with clinical suspicion of wrist injury increases accuracy of fracture detection. This has a significant impact therapy in this population, mainly on cast immobilization.
We registered the study at www.clinicaltrials.gov , NL43482.091.13.
评估单次CT方案作为所有临床怀疑腕部损伤患者的主要成像工具在骨折检测方面的准确性及其治疗影响,并评估其对治疗的最终影响。
我们对所有怀疑腕部和腕骨骨折的患者进行了一项单机构研究。所有患者均接受了传统X线摄影,随后进行了单次腕部CT检查,然后进行了为期1年的随访。医生和放射科医生在CT检查前后采用五点量表对骨折存在的可能性进行前瞻性评分。三位外科医生根据临床和放射学数据提出治疗方案(功能治疗、石膏固定、复位或手术),首先是在了解传统X线摄影的情况下,然后是在了解CT的情况下。骨折存在的参考标准基于所有数据。我们进行了受试者操作特征(ROC)分析,并计算了因CT成像导致治疗改变的腕部比例。
98名患者(63%为女性,平均年龄53岁,范围为18 - 87岁)进行了100次腕部CT检查。传统X线摄影检测出45例真阳性骨折,CT检测出61例。传统X线摄影骨折检测的曲线下面积为0.85(95%CI 0.77 - 0.93),CT为0.97(95%CI 0.93 - 1.00)。24例(24%,95%CI 16 - 33%) - 31例(31%,95%CI 23 - 41%)腕部的治疗发生了改变,主要是石膏固定率降低。
临床怀疑腕部损伤的患者进行单次CT检查可提高骨折检测的准确性。这对该人群的治疗有显著影响,主要是对石膏固定方面。