小柴胡汤治疗12岁以下儿童普通感冒：随机对照试验的系统评价与Meta分析
Soshiho-tang for treating common cold in children younger than 12 years: A systematic review and meta-analysis of randomized controlled trials.
作者信息
Jung Jieun, Park Jihun, Choi Jun-Yong, Lee Ju Ah
机构信息
College of Korean Medicine, Gachon University, Seongnam.
Korean Medicine Hospital of Pusan National University.
出版信息
Medicine (Baltimore). 2018 Nov;97(45):e13045. doi: 10.1097/MD.0000000000013045.
BACKGROUND
Soshiho-tang (SST) is widely used to treat common cold in East Asian countries. Many clinical trials assessing the efficacy and safety of SST formulas for the treatment of pediatric common cold have been reported. The aim of this systematic review is to assess the available clinical evidence on the use of SST formulas in the treatment for common cold in children younger than 12 years.
METHODS
Fifteen databases will be searched from their inception until March 2019. We will be including the randomized controlled trials (RCTs) assessing all types of SST formulas used in the treatment of common cold in children younger than 12 years. The methodological qualities of the RCTs will be assessed using the Cochrane Collaboration tool for assessing the risk of bias, while confidence in the cumulative evidence will be evaluated using the Grading of Recommendations Assessment, Development and Evaluation instrument.
ETHICS AND DISSEMINATION
This systematic review will be published in a peer-reviewed journal and will also be disseminated electronically and in print. The review will be updated to inform and guide health care practices.
背景
小柴胡汤（SST）在东亚国家被广泛用于治疗普通感冒。已有许多评估SST配方治疗小儿普通感冒疗效和安全性的临床试验报告。本系统评价的目的是评估使用SST配方治疗12岁以下儿童普通感冒的现有临床证据。
方法
检索15个数据库自建库至2019年3月的数据。我们将纳入评估所有用于治疗12岁以下儿童普通感冒的SST配方的随机对照试验（RCT）。使用Cochrane协作网评估偏倚风险的工具评估RCT的方法学质量，同时使用推荐分级评估、制定与评价工具评估对累积证据的信心。
伦理与传播
本系统评价将发表在同行评审期刊上，也将以电子和印刷形式传播。该评价将进行更新，以告知和指导医疗实践。
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