USDA-ARS Corn Insects and Crop Genetics Research Unit, Ames, IA 50011, USA.
Department of Ecology, Evolution and Organismal Biology, Iowa State University, Ames, IA 50011, USA.
Nucleic Acids Res. 2019 Jan 8;47(D1):D1146-D1154. doi: 10.1093/nar/gky1046.
Since its 2015 update, MaizeGDB, the Maize Genetics and Genomics database, has expanded to support the sequenced genomes of many maize inbred lines in addition to the B73 reference genome assembly. Curation and development efforts have targeted high quality datasets and tools to support maize trait analysis, germplasm analysis, genetic studies, and breeding. MaizeGDB hosts a wide range of data including recent support of new data types including genome metadata, RNA-seq, proteomics, synteny, and large-scale diversity. To improve access and visualization of data types several new tools have been implemented to: access large-scale maize diversity data (SNPversity), download and compare gene expression data (qTeller), visualize pedigree data (Pedigree Viewer), link genes with phenotype images (MaizeDIG), and enable flexible user-specified queries to the MaizeGDB database (MaizeMine). MaizeGDB also continues to be the community hub for maize research, coordinating activities and providing technical support to the maize research community. Here we report the changes MaizeGDB has made within the last three years to keep pace with recent software and research advances, as well as the pan-genomic landscape that cheaper and better sequencing technologies have made possible. MaizeGDB is accessible online at https://www.maizegdb.org.
自 2015 年更新以来，玉米遗传学和基因组学数据库 MaizeGDB 除了 B73 参考基因组组装外，还扩展到支持许多玉米自交系的测序基因组。编目和开发工作的重点是高质量数据集和工具，以支持玉米性状分析、种质资源分析、遗传研究和育种。MaizeGDB 托管了广泛的数据，包括最近支持的新数据类型，包括基因组元数据、RNA-seq、蛋白质组学、同线性和大规模多样性。为了提高数据类型的访问和可视化，已经实现了几个新工具来：访问大规模玉米多样性数据（SNPversity）、下载和比较基因表达数据（qTeller）、可视化系谱数据（系谱查看器）、将基因与表型图像链接（MaizeDIG），并使 MaizeGDB 数据库能够灵活地执行用户指定的查询（MaizeMine）。MaizeGDB 仍然是玉米研究的社区中心，协调活动并为玉米研究社区提供技术支持。在这里，我们报告了 MaizeGDB 在过去三年中为适应最近的软件和研究进展以及更便宜、更好的测序技术所带来的全基因组景观而做出的改变。MaizeGDB 可在线访问，网址为 https://www.maizegdb.org。
