Gholampourkashi Sara, Cygler Joanna E, Belec Jason, Vujicic Miro, Heath Emily
Carleton Laboratory for Radiotherapy Physics, Carleton University, Ottawa, ON, Canada.
Department of Physics, Carleton University, Ottawa, ON, Canada.
J Appl Clin Med Phys. 2019 Jan;20(1):55-67. doi: 10.1002/acm2.12485. Epub 2018 Nov 8.
To explain the deviation observed between measured and Monaco calculated dose profiles for a small field (i.e., alternating open-closed MLC pattern). A Monte Carlo (MC) model of an Elekta Infinity linac with Agility MLC was created and validated against measurements. In addition, an analytic model which predicts the fluence at the isocenter plane was used to study the impact of multiple beam parameters on the accuracy of dose calculations for small fields.
A detailed MC model of a 6 MV Elekta Infinity linac with Agility MLC was created in EGSnrc/BEAMnrc and validated against measurements. An analytic model using primary and secondary virtual photon sources was created and benchmarked against the MC simulations and the impact of multiple beam parameters on the accuracy of the model for a small field was investigated. Both models were used to explain discrepancies observed between measured/EGSnrc simulated and Monaco calculated dose profiles for alternating open-closed MLC leaves.
MC-simulated dose profiles (PDDs, cross- and in-line profiles, etc.) were found to be in very good agreements with measurements. The best fit for the leaf bank rotation was found to be 9 mrad to model the defocusing of Agility MLC. Moreover, a very good agreement was observed between results from the analytic model and MC simulations for a small field. Modifying the radial size of the incident electron beam in the BEAMnrc model improved the agreement between Monaco and EGSnrc calculated dose profiles by approximately 16% and 30% in the position of maxima and minima, respectively.
Accurate modeling of the full-width-half-maximum (FWHM) of the primary photon source as well as the MLC leaf design (leaf bank rotation, etc.) is essential for accurate calculations of dose delivered by small radiation fields when using virtual source or MC models of the beam.
解释在小射野(即交替开闭的多叶准直器模式)下测量剂量分布与Monaco计算剂量分布之间观察到的偏差。创建了带有Agility多叶准直器的Elekta Infinity直线加速器的蒙特卡罗(MC)模型,并与测量结果进行了验证。此外,使用预测等中心平面注量的解析模型来研究多个射束参数对小射野剂量计算准确性的影响。
在EGSnrc/BEAMnrc中创建了带有Agility多叶准直器的6MV Elekta Infinity直线加速器的详细MC模型,并与测量结果进行了验证。创建了使用初级和次级虚拟光子源解析模型,并与MC模拟进行了基准测试,研究了多个射束参数对小射野模型准确性的影响。两个模型都用于解释在交替开闭的多叶准直器叶片测量/EGSnrc模拟剂量分布与Monaco计算剂量分布之间观察到的差异。
发现MC模拟的剂量分布(百分深度剂量、交叉和轴向分布等)与测量结果非常吻合。发现叶库旋转的最佳拟合值为9毫弧度,以模拟Agility多叶准直器的散焦。此外,对于小射野,解析模型结果与MC模拟结果之间观察到非常好的一致性。在BEAMnrc模型中修改入射电子束的径向尺寸,分别使Monaco和EGSnrc计算的剂量分布在最大值和最小值位置的一致性提高了约16%和30%。
当使用射束的虚拟源或MC模型时,对初级光子源的半高宽(FWHM)以及多叶准直器叶片设计(叶库旋转等)进行精确建模对于准确计算小辐射野输送的剂量至关重要。