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使用二维(2D)二极管阵列MapCHECK2对复杂放射治疗计划进行多叶准直器建模与调试

Multileaf Collimator Modeling and Commissioning for Complex Radiation Treatment Plans Using 2-Dimensional (2D) Diode Array MapCHECK2.

作者信息

Guo Jian, Zhu Meng, Zeng Weijin, Wang He, Qin Songbing, Li Zhibin, Tang Yu, Ying Binbin, Sang Jiugao, Ji Ming, Meng Kuo, Hui Zhouguang, Wang Jianyang, Zhou Juying, Zhou Yin, Huan Jian

机构信息

Department of Radiation Oncology, The First Affiliated Hospital of Soochow University, Suzhou, China.

Qiusuo Health Technologies Inc., Suzhou, China.

出版信息

Technol Cancer Res Treat. 2024 Jan-Dec;23:15330338231225864. doi: 10.1177/15330338231225864.

Abstract

This study aims to develop a data-collecting package ExpressMLC and investigate the applicability of MapCHECK2 for multileaf collimator (MLC) modeling and commissioning for complex radiation treatment plans. The MLC model incorporates realistic parameters to account for sophisticated MLC features. A set of 8 single-beam plans, denoted by ExpressMLC, is created for the determination of parameters. For the commissioning of the MLC model, 4 intensity modulated radiation therapy (IMRT) plans specified by the AAPM TG 119 report were transferred to a computed tomography study of MapCHECK2, recalculated, and compared to measurements on a Varian accelerator. Both per-beam and composite-beam dose verification were conducted. Through sufficient characterization of the MLC model, under 3%/2 mm and 2%/2 mm criteria, MapCHECK2 can be used to accurately verify per beam dose with gamma passing rate better than 90.9% and 89.3%, respectively, while the Gafchromic EBT3 films can achieve gamma passing rate better than 89.3% and 85.7%, respectively. Under the same criteria, MapCHECK2 can achieve composite beam dose verification with a gamma passing rate better than 95.9% and 90.3%, while the Gafchromic EBT3 films can achieve a gamma passing rate better than 96.1% and 91.8%; the -value from the Mann Whitney test between gamma passing rates of the per beam dose verification using full MapCHECK2 package calibrated MLC model and film calibrated MLC model is .44 and .47, respectively; the -value between those of the true composite beam dose verification is .62 and .36, respectively. It is confirmed that the 2-dimensional (2D) diode array MapCHECK2 can be used for data collection for MLC modeling with the combination of the ExpressMLC package of plans, whose doses are sufficient for the determination of MLC parameters. It could be a fitting alternative to films to boost the efficiency of MLC modeling and commissioning without sacrificing accuracy.

摘要

本研究旨在开发一个数据收集软件包ExpressMLC,并研究MapCHECK2在复杂放射治疗计划的多叶准直器(MLC)建模和调试中的适用性。MLC模型纳入了实际参数以考虑复杂的MLC特征。创建了一组8个单束计划(由ExpressMLC表示)用于确定参数。为了调试MLC模型,将美国医学物理师协会(AAPM)TG 119报告指定的4个调强放射治疗(IMRT)计划转移到MapCHECK2的计算机断层扫描研究中,重新计算,并与瓦里安加速器上的测量结果进行比较。进行了逐束和复合束剂量验证。通过对MLC模型的充分表征,在3%/2毫米和2%/2毫米标准下,MapCHECK2可用于准确验证每束剂量,伽马通过率分别优于90.9%和89.3%,而Gafchromic EBT3胶片的伽马通过率分别优于89.3%和85.7%。在相同标准下,MapCHECK2可实现复合束剂量验证,伽马通过率优于95.9%和90.3%,而Gafchromic EBT3胶片的伽马通过率优于96.1%和91.8%;使用完整MapCHECK2软件包校准的MLC模型和胶片校准的MLC模型进行每束剂量验证的伽马通过率之间的曼-惠特尼检验的p值分别为0.44和0.47;真实复合束剂量验证的p值分别为0.62和0.36。证实了二维(2D)二极管阵列MapCHECK2可与ExpressMLC计划软件包结合用于MLC建模的数据收集,其剂量足以确定MLC参数。它可能是胶片的合适替代品,可在不牺牲准确性的情况下提高MLC建模和调试的效率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78a8/10846010/71aabf109436/10.1177_15330338231225864-fig1.jpg

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