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新西兰不存在人类嗜T淋巴细胞病毒I型。

Absence of HTLV I from New Zealand.

作者信息

Reddy D, Okochi K, Woodfield D G, Judd W

出版信息

J Med Virol. 1987 Aug;22(4):375-8. doi: 10.1002/jmv.1890220410.

Abstract

Sera from 1,943 individuals from Auckland, New Zealand, were tested for the presence of serum antibodies to human T cell lymphotropic virus I (HTLV I), mainly with an enzyme-linked immunosorbent assay (ELISA) with cell extracts as target antigen. The individuals tested were blood donors and mostly Caucasian, but included indigenous Maoris and representatives of several groups of Pacific islanders now resident in New Zealand. Also included were 37 patients with various hematological malignancies, including seven with T cell leukemias. Although 1% of samples were positive by ELISA, none of these were confirmed as positives by Western blotting. On the basis of these results we consider that it is unlikely that HTLV I infection occurs in Auckland; however, we cannot exclude the possibility that pockets of virus infection may occur in other parts of New Zealand or the South Pacific.

摘要

对来自新西兰奥克兰的1943人的血清进行了检测,以确定是否存在针对人类嗜T细胞病毒I型(HTLV I)的血清抗体,主要采用以细胞提取物为靶抗原的酶联免疫吸附测定(ELISA)。接受检测的个体为献血者,大多是白种人,但包括原住民毛利人和现居住在新西兰的几组太平洋岛民的代表。还包括37例患有各种血液系统恶性肿瘤的患者,其中7例患有T细胞白血病。虽然ELISA检测中有1%的样本呈阳性,但经蛋白质印迹法确认均无阳性。基于这些结果,我们认为奥克兰不太可能发生HTLV I感染;然而,我们不能排除在新西兰其他地区或南太平洋可能存在病毒感染聚集区的可能性。

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