2型糖尿病患者的听觉晚期潜伏期反应
Auditory Late Latency Response in Individuals with Type 2 Diabetes Mellitus.
作者信息
Kumar Kaushlendra, Bhat Jayashree, Varghese Ancy
机构信息
Kasturba Medical College, Manipal Academy of Higher Education, Mangalore, Audiology and Speech Language Pathology, Karnataka, India.
出版信息
J Int Adv Otol. 2018 Dec;14(3):408-411. doi: 10.5152/iao.2018.3201.
OBJECTIVES
The study was done to compare Auditory late latency response (ALLR) in normal-hearing individuals without diabetes mellitus and normal-hearing individuals with type 2 diabetes mellitus (T2DM).
MATERIALS AND METHODS
A total of 50 participants within the age range of 40-60 years were enrolled in the study based on the inclusion and exclusion criteria. They were divided into two groups with one group consisting of 25 individuals with T2DM and the other group consisted of 25 individuals without diabetes as the control group.
RESULTS
The results revealed prolonged latencies and reduced amplitude of P1, N1 and P2 wave among individuals with T2DM compared to control group. There was a significant positive correlation observed for ALLR latency and duration of T2DM, and a negative correlation observed for ALLR amplitude and duration of T2DM.
CONCLUSION
The present study concluded that there is a problem in the encoding of speech at the cortical level despite normal hearing in individuals with type 2 diabetes mellitus.
目的
本研究旨在比较非糖尿病的听力正常个体与2型糖尿病（T2DM）听力正常个体的听觉晚期潜伏期反应（ALLR）。
材料与方法
根据纳入和排除标准，共招募了50名年龄在40 - 60岁之间的参与者。他们被分为两组，一组由25名T2DM患者组成，另一组由25名无糖尿病个体作为对照组。
结果
结果显示，与对照组相比，T2DM患者的P1、N1和P2波潜伏期延长，波幅降低。ALLR潜伏期与T2DM病程呈显著正相关，ALLR波幅与T2DM病程呈负相关。
结论
本研究得出结论，2型糖尿病患者尽管听力正常，但在皮层水平的言语编码存在问题。
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