Reina Simona, Palombo Denise, Boscaneanu Alexandru, Solari Nicola, Bertoglio Sergio, Valle Luca, Cafiero Ferdinando
Department of Surgery, Chirurgia I- Ospedale Policlinico San Martino Genoa, Italy.
Department of Surgery, Chirurgia I- Ospedale Policlinico San Martino Genoa, Italy; Department of Surgical Sciences and Integrated Diagnostics (DISC) Genoa University, Italy.
Int J Surg Case Rep. 2018;53:196-199. doi: 10.1016/j.ijscr.2018.10.047. Epub 2018 Oct 31.
Eccrine porocarcinoma (EPC) is a slow-growing carcinoma arising from the eccrine sweat glands. Based on its clinical presentation it can be confused with malignant and benign skin lesions, both. Histological examination is essential to formulate a correct diagnosis. Surgical excision with clear margins is the standard therapeutic approach while the role of sentinel lymph node biopsy (SNLB) remains controversial.
The Authors report two cases of EPC of the lower limbs occurred in two women. Patients were treated by wide surgical excision of the lesion and SNLB. 6 months follow-up was disease free for both patients.
Although a rare cutaneous tumor, EPC has to be taken into account in the differential diagnosis of malignant skin lesions because of its possible loco-regional aggressiveness and related morbidity. Among the available treatment options, surgical excision is considered the standard approach whereas the role of SNLB is controversial although the Authors discuss a possible usefulness for staging and diagnosis.
小汗腺汗孔癌(EPC)是一种起源于小汗腺的生长缓慢的癌症。基于其临床表现,它可能会与恶性和良性皮肤病变相混淆。组织学检查对于做出正确诊断至关重要。切缘清晰的手术切除是标准的治疗方法,而前哨淋巴结活检(SNLB)的作用仍存在争议。
作者报告了两例发生在两名女性身上的下肢EPC病例。患者接受了病变的广泛手术切除和SNLB。两名患者均随访6个月,无疾病复发。
尽管EPC是一种罕见的皮肤肿瘤,但由于其可能的局部侵袭性和相关发病率,在恶性皮肤病变的鉴别诊断中必须考虑到它。在现有的治疗选择中,手术切除被认为是标准方法,而SNLB的作用存在争议,尽管作者讨论了其在分期和诊断方面可能的有用性。