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1
Use of Integra dermal substitute to prevent implantable device extrusion in an Olympic athlete.使用Integra真皮替代物预防一名奥运运动员体内植入设备的挤出。
BMJ Case Rep. 2018 Nov 8;2018:bcr-2018-226181. doi: 10.1136/bcr-2018-226181.
2
[The use of Integra dermal regeneration matrix in the surgical treatment of a recurrent, extensive, malignant skin lesion in the temporal region].[Integra真皮再生基质在颞部复发性广泛性恶性皮肤病变手术治疗中的应用]
Orv Hetil. 2013 Feb 10;154(6):225-7. doi: 10.1556/OH.2013.29535.
3
Compared to coverage by STSG grafts only reconstruction by the dermal substitute Integra® plus STSG increases TcPO2 values in diabetic feet at 3 and 6 months after reconstruction*.与仅使用自体皮片移植覆盖相比，使用真皮替代物Integra®加自体皮片移植进行重建可提高糖尿病足重建后3个月和6个月时的经皮氧分压（TcPO2）值*。
G Chir. 2014 May-Jun;35(5-6):141-5.
4
Tendon coverage using an artificial skin substitute.使用人工皮肤替代物覆盖肌腱。
J Plast Reconstr Aesthet Surg. 2012 Nov;65(11):1544-50. doi: 10.1016/j.bjps.2012.05.021. Epub 2012 Jun 20.
5
[Use of Integra in a case of extensive upper extremity avulsion].[Integra在一例上肢广泛撕脱伤中的应用]
Orv Hetil. 2011 Sep 4;152(36):1443-6. doi: 10.1556/OH.2011.29190.
6
An objective long-term evaluation of Integra (a dermal skin substitute) and split thickness skin grafts, in acute burns and reconstructive surgery.真皮替代物 Integra 与断层皮片在急性烧伤和整形术中的客观长期评价。
Burns. 2010 Feb;36(1):23-8. doi: 10.1016/j.burns.2009.07.011. Epub 2009 Oct 27.
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Use of Integra in complex pediatric wounds.Integra在小儿复杂伤口中的应用。
Ann Plast Surg. 2011 May;66(5):493-6. doi: 10.1097/SAP.0b013e318203ea4e.
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[The role of Integra dermal regeneration matrix in skin replacement on the upper extremity].[Integra真皮再生基质在上肢皮肤替代中的作用]
Orv Hetil. 2012 Aug 26;153(34):1351-5. doi: 10.1556/OH.2012.29438.
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The Use of Integra Dermal Regeneration Template Versus Flaps for Reconstruction of Full-Thickness Scalp Defects Involving the Calvaria: A Cost-Benefit Analysis.使用Integra真皮再生模板与皮瓣修复累及颅骨的全层头皮缺损：成本效益分析
Aesthetic Plast Surg. 2016 Dec;40(6):901-907. doi: 10.1007/s00266-016-0703-0. Epub 2016 Oct 3.
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Integra--a therapeutic alternative in reconstructive surgery. Our first experience.Integra——重建手术中的一种治疗选择。我们的首次经验。
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本文引用的文献

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Long-term outcomes of continuous intrathecal baclofen infusion for treatment of spasticity: a prospective multicenter follow-up study.鞘内持续输注巴氯芬治疗痉挛的长期疗效：一项前瞻性多中心随访研究。
Neuromodulation. 2008 Jul;11(3):227-36. doi: 10.1111/j.1525-1403.2008.00170.x.
2
Reconstructive surgery with Integra dermal regeneration template: histologic study, clinical evaluation, and current practice.使用Integra真皮再生模板的重建手术：组织学研究、临床评估及当前实践。
Plast Reconstr Surg. 2006 Jun;117(7 Suppl):160S-174S. doi: 10.1097/01.prs.0000222609.40461.68.
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Baclofen pump pocket infection: a case report of successful salvage with muscle flap.巴氯芬泵囊袋感染：一例采用肌瓣成功挽救的病例报告
Int Wound J. 2006 Mar;3(1):23-8. doi: 10.1111/j.1742-4801.2006.00179.x.
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Identification and management of intrathecal baclofen pump complications: a comparison of pediatric and adult patients.鞘内注射巴氯芬泵并发症的识别与处理：儿童与成人患者的比较
J Neurosurg. 2006 Jan;104(1 Suppl):9-15. doi: 10.3171/ped.2006.104.1.9.
5
Multicenter postapproval clinical trial of Integra dermal regeneration template for burn treatment.用于烧伤治疗的Integra真皮再生模板的多中心批准后临床试验。
J Burn Care Rehabil. 2003 Jan-Feb;24(1):42-8. doi: 10.1097/00004630-200301000-00009.
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Design of an artificial skin. I. Basic design principles.人工皮肤的设计。I. 基本设计原则。
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Scar repair by the double-breasted vest principle.采用双排扣背心原理进行瘢痕修复。
Plast Reconstr Surg. 1970 Jun;45(6):616-9. doi: 10.1097/00006534-197006000-00021.

使用Integra真皮替代物预防一名奥运运动员体内植入设备的挤出。

Use of Integra dermal substitute to prevent implantable device extrusion in an Olympic athlete.

作者信息

Page Felicity, Patel Krupali, Jaffe Wayne

机构信息

Plastic Surgery Department, Royal Stoke University Hospital, Stoke-on-Trent, UK.

出版信息

BMJ Case Rep. 2018 Nov 8;2018:bcr-2018-226181. doi: 10.1136/bcr-2018-226181.

DOI:10.1136/bcr-2018-226181
PMID:30413448
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6229092/
Abstract

We present a challenging case of imminent metallic implant extrusion in a Paralympic athlete managed with a single-stage procedure using 'Integra' dermal substitute. The patient had hereditary spastic paraparesis, for which a baclofen pump delivering intrathecal medication was vital in the management of his condition. The device had been most recently implanted into the thigh after previous complications. Integra provided robust soft-tissue coverage over the implanted baclofen pump in the thigh. Different operative management strategies were considered but the use of Integra was felt to offer the least morbidity and a quick recovery. The patient was able to successfully compete in a Paralympic canoeing qualifying event the week following surgery and achieve medal success. To the authors' knowledge, this is first case in which Integra has been used in such circumstances.

摘要

我们展示了一例具有挑战性的病例，一名残奥会运动员面临金属植入物即将挤出的情况，通过使用 “Integra” 真皮替代物的单阶段手术进行处理。该患者患有遗传性痉挛性截瘫，对于他的病情管理而言，输送鞘内药物的巴氯芬泵至关重要。该装置在先前出现并发症后最近植入大腿。Integra为大腿中植入的巴氯芬泵提供了强大的软组织覆盖。考虑了不同的手术管理策略，但使用Integra被认为发病率最低且恢复迅速。患者在手术后一周能够成功参加残奥会皮划艇资格赛并获得奖牌。据作者所知，这是Integra在这种情况下首次被使用的病例。