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酿酒酵母(Saccharomyces cerevisiae)染色体III上DNA复制起点与自主复制序列(ARS)元件的紧密关联。

Close association of a DNA replication origin and an ARS element on chromosome III of the yeast, Saccharomyces cerevisiae.

作者信息

Huberman J A, Zhu J G, Davis L R, Newlon C S

机构信息

Department of Molecular and Cellular Biology, Roswell Park Memorial Institute, Buffalo, NY 14263.

出版信息

Nucleic Acids Res. 1988 Jul 25;16(14A):6373-84. doi: 10.1093/nar/16.14.6373.

Abstract

Two dimensional gel electrophoretic techniques were used to locate all functional DNA replication origins in a 22.5 kb stretch of yeast chromosome III. Only one origin was detected, and that origin is located within several hundred bp of an ARS element.

摘要

二维凝胶电泳技术被用于定位酵母三号染色体22.5 kb片段中的所有功能性DNA复制起点。仅检测到一个起点,且该起点位于一个自主复制序列(ARS)元件的几百个碱基对范围内。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89e5/338302/f0f6b4ca62fa/nar00167-0123-a.jpg

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