Department of Neurology and Laboratory of Functional Neurosciences (EA 4559), University Hospital of Amiens, France.
Department of Neurology, Rouen University Hospital, Rouen, France.
Cortex. 2018 Dec;109:322-335. doi: 10.1016/j.cortex.2018.09.026. Epub 2018 Oct 17.
Although executive function disorders are among the most prevalent cognitive impairments a consensus on diagnostic criteria has yet to be reached. With a view to harmonizing these criteria, the present position paper (i) focuses on the main dysexecutive disorders, (ii) examines recent approaches in both the behavioral and cognitive domains, (iii) defines diagnostic boundaries for frontal syndrome, (iv) reports on the frequency and profile of the executive function disorders observed in the main brain diseases, and (v) proposes an operationalization of diagnostic criteria. Future work must define the executive processes involved in human adaptive behavior, characterize their impairment in brain diseases, and improve the management of these conditions (including remediation strategies and rehabilitation).
虽然执行功能障碍是最常见的认知障碍之一,但尚未就诊断标准达成共识。本立场文件旨在(i)关注主要的执行功能障碍,(ii)检查行为和认知领域的最新方法,(iii)定义额综合征的诊断界限,(iv)报告主要脑部疾病中观察到的执行功能障碍的频率和特征,以及(v)提出诊断标准的操作化。未来的工作必须确定涉及人类适应行为的执行过程,描述它们在脑部疾病中的损伤,并改善这些疾病的管理(包括矫正策略和康复)。