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A case of combined Merkel cell carcinoma and squamous cell carcinoma: Molecular insights and diagnostic pitfalls.

作者信息

Falto Aizpurua Leyre A, Wang Min, Ruiz Hiram A, Sánchez Jorge L, Chan May P, Andea Aleodor A, Harms Paul W

机构信息

Department of Dermatology, University of Puerto Rico, Medical Sciences Campus, San Juan, Puerto Rico.

Department of Pathology, University of Michigan, Ann Arbor, Michigan.

出版信息

JAAD Case Rep. 2018 Nov 3;4(10):996-999. doi: 10.1016/j.jdcr.2018.08.004. eCollection 2018 Nov.

DOI:10.1016/j.jdcr.2018.08.004
PMID:30417062
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6216094/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa21/6216094/47db14f4bf78/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa21/6216094/de1083abeff8/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa21/6216094/0faa13b48788/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa21/6216094/8067d07cc16d/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa21/6216094/47db14f4bf78/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa21/6216094/de1083abeff8/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa21/6216094/0faa13b48788/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa21/6216094/8067d07cc16d/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa21/6216094/47db14f4bf78/gr4.jpg

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Hum Pathol. 2018 Jan;71:117-125. doi: 10.1016/j.humpath.2017.10.014. Epub 2017 Oct 24.
2
Update on Merkel Cell Carcinoma.默克尔细胞癌的最新进展
Clin Lab Med. 2017 Sep;37(3):485-501. doi: 10.1016/j.cll.2017.05.004. Epub 2017 Jun 13.
3
Molecular Profiling of Multiple Primary Merkel Cell Carcinoma to Distinguish Genetically Distinct Tumors From Clonally Related Metastases.
直接细胞重编程可使携带病毒 T 抗原的小鼠发展为 Merkel 细胞癌。
J Clin Invest. 2022 Apr 1;132(7). doi: 10.1172/JCI152069.
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Genomic evidence suggests that cutaneous neuroendocrine carcinomas can arise from squamous dysplastic precursors.基因组证据表明，皮肤神经内分泌癌可能起源于鳞状发育不良前体。
Mod Pathol. 2022 Apr;35(4):506-514. doi: 10.1038/s41379-021-00928-1. Epub 2021 Sep 30.
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Histogenesis of Merkel Cell Carcinoma: A Comprehensive Review.默克尔细胞癌的组织发生：全面综述
Front Oncol. 2019 Jun 10;9:451. doi: 10.3389/fonc.2019.00451. eCollection 2019.
多原发性默克尔细胞癌的分子剖析，以区分基因上不同的肿瘤与克隆相关的转移灶。
JAMA Dermatol. 2017 Jun 1;153(6):505-512. doi: 10.1001/jamadermatol.2017.0507.
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Multiple Merkel cell carcinomas: Late metastasis or multiple primary tumors? A molecular study.多发性默克尔细胞癌：晚期转移还是多原发性肿瘤？一项分子研究。
JAAD Case Rep. 2017 Mar 20;3(2):131-134. doi: 10.1016/j.jdcr.2017.01.011. eCollection 2017 Mar.
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Merkel cell carcinoma: Epidemiology, prognosis, therapy and unmet medical needs.默克尔细胞癌：流行病学、预后、治疗和未满足的医疗需求。
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Cutaneous squamous and neuroendocrine carcinoma: genetically and immunohistochemically different from Merkel cell carcinoma.皮肤鳞状和神经内分泌癌：在基因和免疫组织化学方面与默克尔细胞癌不同。
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An isolated Merkel cell carcinoma metastasis at a distant cutaneous site presenting as a second 'primary' tumor.一个孤立的默克尔细胞癌转移灶出现在远处皮肤部位，表现为第二个“原发性”肿瘤。
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Distinction of 2 different primary Merkel cell carcinomas in 1 patient by Merkel cell polyomavirus genome analysis.通过默克尔细胞多瘤病毒基因组分析鉴别1例患者的2种不同原发性默克尔细胞癌。
Arch Dermatol. 2010 Jun;146(6):687-9. doi: 10.1001/archdermatol.2010.121.
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