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2
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Biostatistics. 2019 Apr 1;20(2):273-286. doi: 10.1093/biostatistics/kxx069.
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Phase I Trial of M7824 (MSB0011359C), a Bifunctional Fusion Protein Targeting PD-L1 and TGFβ, in Advanced Solid Tumors.M7824(MSB0011359C)的 I 期临床试验,一种双功能融合蛋白,靶向 PD-L1 和 TGFβ,用于晚期实体瘤。
Clin Cancer Res. 2018 Mar 15;24(6):1287-1295. doi: 10.1158/1078-0432.CCR-17-2653. Epub 2018 Jan 3.
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Cancer immunotherapies targeting the PD-1 signaling pathway.靶向PD-1信号通路的癌症免疫疗法。
J Biomed Sci. 2017 Apr 4;24(1):26. doi: 10.1186/s12929-017-0329-9.
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MUC1-C Oncoprotein Integrates a Program of EMT, Epigenetic Reprogramming and Immune Evasion in Human Carcinomas.MUC1-C 癌蛋白在人类癌中整合 EMT、表观遗传重编程和免疫逃逸程序。
Biochim Biophys Acta Rev Cancer. 2017 Aug;1868(1):117-122. doi: 10.1016/j.bbcan.2017.03.003. Epub 2017 Mar 14.
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Phase I Trial of a Yeast-Based Therapeutic Cancer Vaccine (GI-6301) Targeting the Transcription Factor Brachyury.靶向转录因子 Brachyury 的酵母基治疗性癌症疫苗(GI-6301)的 I 期临床试验。
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Placebo-controlled phase III trial of immunologic therapy with sipuleucel-T (APC8015) in patients with metastatic, asymptomatic hormone refractory prostate cancer.在转移性、无症状激素难治性前列腺癌患者中进行的西妥昔单抗-T(APC8015)免疫治疗的安慰剂对照III期试验。
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Vaccines as an Integral Component of Cancer Immunotherapy.

作者信息

Schlom Jeffrey, Gulley James L

机构信息

Laboratory of Tumor Immunology and Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.

Genitourinary Malignancies Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.

出版信息

JAMA. 2018 Dec 4;320(21):2195-2196. doi: 10.1001/jama.2018.9511.

DOI:10.1001/jama.2018.9511
PMID:30419097
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6538063/
Abstract
摘要