Grossman C M
Atherosclerosis. 1988 Jun;71(2-3):193-5. doi: 10.1016/0021-9150(88)90143-8.
Intra-individual variations of serum cholesterol levels were examined retrospectively over a period of 1-12 years in 77 office patients. The findings confirm for patients the variations published in the literature on volunteers. There was apparently more than one population, one with small variances and another with much greater variances. Because of the large variances in many patients, a physician should obtain several independent measures before attempting to evaluate any therapeutic program.
对77名门诊患者1至12年期间的血清胆固醇水平个体内变异进行了回顾性研究。研究结果证实了文献中报道的志愿者的变异情况同样适用于患者。显然存在不止一种人群，一种人群的变异较小，另一种人群的变异则大得多。由于许多患者的变异很大，医生在尝试评估任何治疗方案之前应进行多次独立测量。
