Karachalios Charalampos, Bakas Panagiotis, Beta Anastasia, Deligeoroglou Efthimios
Second Department of Obstetrics and Gynecology, Aretaieio University Hospital, Vasilissis Sofias 76, Greece.
Case Rep Womens Health. 2018 Oct 15;20:e00083. doi: 10.1016/j.crwh.2018.e00083. eCollection 2018 Oct.
Postpartum nephrotic syndrome in a pregnant woman with rheumatoid arthritis in long-standing remission is rare. Systemic lupus erythematosus can remain undiagnosed, especially in the absence of clinical manifestations. We present the case of a 34-year-old woman (gravida 2, para 1) who underwent a lower-segment cesarean section at 34 weeks and 6 days of gestation because she had developed preeclampsia and nephrotic syndrome. The concomitant presence of significant hypoproteinemia, hypoalbuminemia, uremia, elevated creatinine serum levels, hyperuricemia and hypertriglyceridemia is indicative of impaired renal function and nephrotic syndrome. This woman was diagnosed with systemic lupus erythematosus nephritis. It is imperative for clinicians to investigate the exact pathophysiological causes of nephrotic syndrome with onset in the puerperium and implement the appropriate therapeutic regimens.
一名处于长期缓解期的类风湿关节炎孕妇发生产后肾病综合征的情况较为罕见。系统性红斑狼疮可能未被诊断出来,尤其是在没有临床表现的情况下。我们报告一例34岁女性(孕2产1)的病例,该女性在妊娠34周6天时因出现先兆子痫和肾病综合征而接受了下段剖宫产术。同时存在的显著低蛋白血症、低白蛋白血症、尿毒症、血清肌酐水平升高、高尿酸血症和高甘油三酯血症提示肾功能受损和肾病综合征。该女性被诊断为系统性红斑狼疮肾炎。临床医生必须调查产褥期发病的肾病综合征的确切病理生理原因,并实施适当的治疗方案。