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体外受精与胚胎移植后腹腔妊娠

Abdominal pregnancy after in vitro fertilization and embryo transfer.

作者信息

Oehninger S, Kreiner D, Bass M J, Rosenwaks Z

机构信息

Jones Institute for Reproductive Medicine, Eastern Virginia Medical School, Norfolk.

出版信息

Obstet Gynecol. 1988 Sep;72(3 Pt 2):499-502.

PMID:3043301
Abstract

Ectopic pregnancy continues to be a major complication of in vitro fertilization (IVF) and embryo transfer. We report the first abdominal pregnancy occurring after this therapeutic approach. The patient, a 35-year-old female, presented a frozen pelvis with a history of severe endometriosis and a left salpingectomy. After the transfer of four concepti in her second IVF/embryo transfer attempt, she became pregnant. Unfortunately, ultrasound evaluation five weeks later showed an ectopic pregnancy in the cul-de-sac. During laparotomy, it was noticed that implantation had taken place near the mesentery of the sigmoid and rectosigmoid. A right cornual tubal ligation was performed. Although the benefit of IVF/embryo transfer far outweighs the risk of an ectopic pregnancy, it is imperative that physicians who care for patients after IVF/embryo transfer be fully aware of the possibility of this complication in this high-risk population.

摘要

异位妊娠仍然是体外受精(IVF)和胚胎移植的主要并发症。我们报告了首例经这种治疗方法后发生的腹腔妊娠。该患者为一名35岁女性,盆腔粘连严重,有重度子宫内膜异位症病史且行过左侧输卵管切除术。在她第二次IVF/胚胎移植尝试中移植了4个受精卵后,她怀孕了。不幸的是,五周后的超声检查显示在直肠子宫陷凹处有异位妊娠。剖腹手术时发现,着床发生在乙状结肠和直肠乙状结肠系膜附近。进行了右侧输卵管间质部结扎术。尽管IVF/胚胎移植的益处远大于异位妊娠的风险,但IVF/胚胎移植后照料患者的医生必须充分意识到在这个高危人群中发生这种并发症的可能性。

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