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向下凝视障碍:病变的部位与性质

Failure of downward gaze: the site and nature of the lesion.

作者信息

Halmagyi G M, Evans W A, Hallinan J M

出版信息

Arch Neurol. 1978 Jan;35(1):22-6. doi: 10.1001/archneur.1978.00500250026005.

DOI:10.1001/archneur.1978.00500250026005
PMID:304343
Abstract

We report four patients with paralysis of downward gaze but with intact upward gaze, including one with detailed clinico-pathological studies and another with a focal computerized axial tomographic (CT) scan abnormality confirming the presence of bilateral lesions of the dorsomedial red nucleus, including the fasciculus retroflexus. It is suggested that sudden, permanent selective failure of downward gaze accompanied by transient disturbance of consciousness is an embolic syndrome of the posterior thalamosubthalamic or rubral artery.

摘要

我们报告了4例向下凝视麻痹但向上凝视正常的患者,其中1例进行了详细的临床病理研究,另1例经局部计算机断层扫描(CT)异常证实存在双侧背内侧红核病变,包括后屈束。提示突然发生的、永久性的选择性向下凝视障碍并伴有短暂意识障碍是丘脑底后动脉或红核动脉的栓塞综合征。

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1
Failure of downward gaze: the site and nature of the lesion.向下凝视障碍:病变的部位与性质
Arch Neurol. 1978 Jan;35(1):22-6. doi: 10.1001/archneur.1978.00500250026005.
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The lesions producing paralysis of downward but not upward gaze.这些病变导致向下注视麻痹但不导致向上注视麻痹。
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引用本文的文献

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A case of double depressor palsy followed by pursuit deficit due to sequential infarction in bilateral thalamus and right medial superior temporal area.一例双侧丘脑及右侧颞上内侧区相继梗死导致双侧面神经麻痹并伴有追踪功能障碍的病例。
Int Ophthalmol. 2017 Dec;37(6):1353-1363. doi: 10.1007/s10792-016-0407-0. Epub 2016 Dec 5.
2
Topographical organization of cat mesodiencephalic areas for monosynaptic activation of vertical oculomotoneurons.猫中脑和间脑区域对垂直眼球运动神经元单突触激活的拓扑组织。
Exp Brain Res. 1993;94(1):43-52. doi: 10.1007/BF00230469.
3
Paramedian diencephalic syndrome.
旁正中间脑综合征
Ital J Neurol Sci. 1994 Sep;15(6):285-90. doi: 10.1007/BF02339238.
4
Oculomotor abnormalities in patients with lesions involving the tectal region.涉及顶盖区病变患者的动眼神经异常。
Ital J Neurol Sci. 1980 Jun;1(3):139-48. doi: 10.1007/BF02335843.
5
Oblique saccadic eye movements of the cat.猫的斜向扫视眼动
Exp Brain Res. 1981;41(3-4):370-9. doi: 10.1007/BF00238895.
6
Bilateral paramedian thalamic infarctions: a CT study.双侧丘脑旁正中梗死:一项CT研究
Neuroradiology. 1986;28(2):128-31. doi: 10.1007/BF00327884.
7
Bilateral paramedian thalamic artery infarcts: report of eight cases.双侧丘脑旁正中动脉梗死:8例报告
J Neurol Neurosurg Psychiatry. 1987 Jul;50(7):900-9. doi: 10.1136/jnnp.50.7.900.
8
Direct excitatory and inhibitory synaptic inputs from the medial mesodiencephalic junction to motoneurons innervating extraocular oblique muscles in the cat.从猫的中脑间脑内侧连接处到支配眼外斜肌的运动神经元的直接兴奋性和抑制性突触输入。
Exp Brain Res. 1985;61(1):62-72. doi: 10.1007/BF00235621.
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Syndrome of downward gaze paralysis, amnesia and hypersomnolence.向下凝视麻痹、失忆和嗜睡综合征。
Postgrad Med J. 1989 Nov;65(769):840-2. doi: 10.1136/pgmj.65.769.840.
10
Vertical gaze palsy and selective unilateral infarction of the rostral interstitial nucleus of the medial longitudinal fasciculus (riMLF).垂直凝视麻痹与内侧纵束嘴侧间质核(riMLF)的选择性单侧梗死。
J Neurol Neurosurg Psychiatry. 1990 Jan;53(1):67-71. doi: 10.1136/jnnp.53.1.67.