Spataro R F
Department of Radiology, University of Rochester School of Medicine and Dentistry, New York.
Urol Radiol. 1988;10(1):2-5. doi: 10.1007/BF02926526.
In equivalent doses for intravenous urograms conventional ionic contrast agents give iodine concentrations in the urine of approximately 30 mg iodine/ml, nonionic contrast media provide approximately 50 mg iodine/ml, and the ionic dimer Hexabrix approximately 70 mg iodine/mL. These new low osmolality, contrast media provide significantly higher urinary iodine concentrations than conventional ionic contrast media, provide better diagnostic quality excretory urograms, better patient tolerance, and fewer adverse side-effects and serious reactions. These new low osmolality, contrast media have significant advantages in intravenous urography in both safety and efficacy when compared to conventional higher osmolality contrast media.
在用于静脉尿路造影的等效剂量下，传统离子型造影剂使尿液中的碘浓度约为30毫克碘/毫升，非离子型造影剂约为50毫克碘/毫升，离子型二聚体Hexabrix约为70毫克碘/毫升。这些新型低渗造影剂所提供的尿碘浓度明显高于传统离子型造影剂，能提供诊断质量更好的排泄性尿路造影，患者耐受性更好，副作用和严重反应更少。与传统的高渗造影剂相比，这些新型低渗造影剂在静脉尿路造影的安全性和有效性方面均具有显著优势。
